Ten lessons from the book:

“What I Learned Losing a Million Dollars” by Jim Paul and Brendan Moynihan

A thread 🧵👇

“Experience is the worst teacher. It gives the test before giving the lesson.”
“Smart people learn from their mistakes and wise people learn from somebody else’s mistakes.”
“A fool must now and then be right by chance.” - William Cowper
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“Speculating is the application of intellectual examination and systematic analysis to the problem of the uncertain future.”
“Man is extremely uncomfortable with uncertainty. To deal with his discomfort, man tends to create a false sense of security by substituting certainty for uncertainty. It becomes the herd instinct. - Bennett Goodspeed
“There’s nothing worse than two people who have on the same position talking to each other about the position.”
“Success can be built upon repeated failues when the failures aren't taken personally; likewise, failure can be built upon repeated successes when the successes are taken personally.”
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Book link: https://t.co/obUVOG6WIt

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Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.

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Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.


...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.


Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.