https://t.co/LjpdlHa0C7 is getting a good face-lift.
Samples now have variant tables with annotation on their impact to the gene.
There is also an IGV integration. You need IGV installed locally but the Start|Jump links will open up you BAM file in IGV.

Users: hey can you get rid of the Nazis please

Twitter: ok sure, we've changed the stars to hearts for likes

Users: no no, zero Nazis please

Twitter: yep we're getting rid of Vine

Users: nah hey, what about the Nazis

Twitter: ok ok fine, no more likes

Really though, if you had to ask any average user what were the main things leading to a bad "quality of debate" on this bad website, the tiny little heart symbols would not exactly be at the top of most people's lists

Observing the public conversation around FB, and the private ones happening among techies and ex-FBers, I think the mutual misunderstanding is worse than when I set out two years (and 500 pages) ago to (in a small way) bridge that gulf.

We're basically fucked.

The tech world has gotten so huge, self-reinforcing, and insulated from reality they can no longer even vaguely look at themselves (and their actions) as others do. They just live on a different planet than most people.

Conversely, the average tech consumer doesn't understand the technology that has slowly taken over their lives, and their designated emissaries to figure it out--politicians, pundits, regulators, journalists--understand it barely better than they do, and have their own agendas.

To say more than generalities for a moment, here's what I think is likely the core problem.

Techies take weird, improbable visions, and make them realities: some BS pitch deck to a VC, mixed with money and people, really does turn into some novel thing.

Most people work inside a legacy industry that's evolved that way over time (usually for good reasons), and they think about the future via some analogy with their present (which is a function of a long-ago past). The interruption that tech will introduce is often hard to grasp.

Java was first released in mid-1995, just 6 months before JS.

By 98, when I went to college, Java was already used for all the first level courses in the CS program.

How did it catch on so quickly (just 3 years) to shift university curriculum, which is usually so slow/behind?

I wonder why Java was so respected and JS was not? Why/how was Java already seen as such a stable and mature language?

Not just Java, other languages (like python) were also released around/near 95, and also seemed to get to "mature" respect status. much quicker.

I bring all this up because my impression of Java in 98 was that it had been around "forever" (as had C++ first developed in 79, but not standardized until 98!), but that's not. true at all. These were all new languages around the same time.

I'm sure the language designs had different merits, and the target applications meant a different perception and reception, but...

it sure seems like the industry (and academics) just decided Java and C++ were the stable mature ones and langs like JS were toys.

BTW, before you assume JS was nascent/immature b/c the web wasn't much of a thing yet, remember that JS was actually released as LiveScript on the server before it was released in a browser. So "server-side JS" was always part of the story, not just Node 15 years later in 2009.

Last weekend, I made a threat on the ongoing #SocialMedia shutdown in Uganda and some implications on the future of #internet & Uganda's #digital agenda.

The thread attracted a lot of engagement and questions. Tonight, I will share some final thoughts on the subject. (1)

Conceptually, social media sites are the largest on-boarding platforms for internet users in Uganda. Notably, Facebook, WhatsApp, Twitter, Instagram & Snapchat attract the highest internet traffic- which drives demand for other platform services e.g Google and Zoom recently.

So- when we talk about an "open internet", we mean the FULL resources of the internet. Any encumberance on selected applications has ripple effects across the entire network thus jeorpadizing standardization of internet/data transmission which is essential for innovation & growth

Furthermore, shutdowns hinder network interoperability (technical ability to plug/link one digital product or service into another product or service). Interoperability is the heart of the "Internet of things" eg business, devices, networks, services, e-govt, integration etc #IoT

Because the internet is a global resource, shutdowns enhance a digital divide (the gap between demographics and regions that have access to modern ICTs, and those that don't or have restricted access). Ironic that 3rd world countries have the highest number of shutdowns globally.

Ever wondered how the JVM debugger 'Evaluate' feature works in IDEs? Long ago I thought that the Java debug interface (JDI) actually allows you to specify the expression and get back its value.

However, this is not quite possible: there's no Java language compiler inside the JVM. When the process is paused JDI allows you to read or write any variables and fields or even execute an existing method with given arguments. But nothing like addition or multiplication.

On the other hand, #IntelliJIDEA debugger allows you to evaluate even statements! You can write there `for`, `if`, `while`, `switch` - whatever. You can even declare local variables. So how this works?

The answer is simple: IDEA debugger has a built-in interpreter for Java! If you access an existing variable or a field, call a method or instantiate an object, it queries JDI. Otherwise, IDE itself does all the calculations.

The amusing thing is that debugger authors didn't bother to make it as strict as Java itself, so the language inside the interpreter is a much more permissive version of Java. For example, you don't need to initialize variables there! Default values like 0 are used automatically.