HOW TO STAY YOUNG:

Starve-destroy-recycle-eat-build-eat-build-starve...

The human ecosystem (our internal environment) has the same processes as the environmental ecosystem. Destruction & Reconstruction is a universal process. This is how we stay young.

Wonder why your Ph.D./Master's application is being rejected?

Here are some insider reasons (from a committee member) that result in such "Love Letters" 👇

- A Short Thread

1) First, you should know that sometimes, an independent reviewer is required (especially in the US) to review applications even after PIs must have selected their candidates. So, even if any bias slips through the PI, the independent reviewer will pick it up.

2) Having said this, there are three major issues that application reviewers/committees often find with your application. These three components make your applications almost challenging to assess.

3) NUMBER ONE - Incomplete Applications

This occurs when you do not upload the requested documents needed to evaluate your file. Think of a candidate that did not send a GRE score when the institution clearly requires it for admission.

4) NUMBER TWO - Error laden Essays

This is particularly interesting because based on reports from this resource person, it is not particularly about how little your experience is but how you communicate it error-free or at least extensively minimized. This gives headache!

With @franklowery our new study on attributes of T cells that contribute to successful cell therapy in cancer patients in @ScienceMagazine today w/ colleagues @slgoff_SB, @NCI_CCR_SB @theNCI a TL;DR thread on key findings with caveats :) 1/10

has a long history of using tumor infiltrating T cells (TILs) to treat cancers since well.. before I was even born. We analyzed our most successful melanoma ACT trial for cell surface phenotypes in TIL infusion products of patients (aPD1/immunotherapy naive) /2

Surprisingly we found a CD39- TIL subset (CD39-CD69-, DN) associated with ACT-response. TBH we were expecting the opposite (CD39+). We only included CD39 bcz multiple groups (e.g. Simoni et al, 2018) had reported CD39+ as enriching for anti-tumor/neoantigen reactive T cells. /3

CD39- DN TILs RNA/epigenetics resemble stem-like memory progenitors, and in vitro were able to self-renew, and give rise to other CD39+ subsets. OTOH the most dominant subset of patient infusion products were CD39+ CD69+ (DP) and these guys were terminally differentiated.. /4

So, to clarify we specifically analyzed tumor-specific mutation-reactive Tcells. Turns out, ACT-responders had pool of neoantigen-reactive TILs in the CD39- phenotype, while non-responders did not (despite other irrelevant CD39- Tcells) -> not all CD39- T cells are bystanders /5

I think I've permanently confused KiCAD
it's reminding me that I need to connect this capacitor to Nothing

attach this end to ground, this end to +5v, and this end to THE VOID

I accidentally made all the capacitors gigantic and they won't fit anymore

halp

gonna design an ISA card using some of these

it's gonna be tricky to fit in the case

that's from this

These 'Beach Animals' were created by Theo Jansen as a fusion of art and engineering. The kinetic structures walk on their own and get all their energy from the

Watch the full video on Youtube: