https://t.co/DF40S9biYF
Unfortunately the observed ORF8 inactivation or the nsp6 SGF deletion are both indicative of T cell depletion, yet the deletion of HV and Y suggest functional B cell immunity—specifically the HV deletion is not observed in the patient nor the ORF8

Did you know?
Ahilyabai Holkar was one of India's
greatest women rulers of all time.

Ahilyabai was Born on May 31,1725 in the village of Chondi,Jamkhed distt,Maharashtra to a man named Mankoji Shinde,who was the Patil(Chief) of a village and a member of proud Dhangar Community.

Despite the fact that girls' education was a farther dream in those days, Ahilyabai was homeschooled by her father.
Ahilya didn't belong to any royal family but in a twist of fate she is still remembered as one of the most revered Queen in the history.

While they were living their humdrum lives, one day Malhar Rao Holkar, commander of the Peshwa Bajirao & Lord of the Malwa stopped in Chondi on his way to Pune, where he couldn't help but notice a young 8yrs old Ahilyabai in the temple service feeding the poor & hungry.

He was so impressed by the sheer innocence&beauty with simplicity character of Ahilyabai dat he asked her hand in marriage for his son Khanderao Holkar.Just like that she got married to Khanderao in 1733 at a tender age of 8&became a bride of esteemed Maratha community of Holkars

But destiny had something else in store for her as her husband died in the Battle of Kumbher in 1754 leaving her widow at 29.Distressed Ahilyabai was to commit Sati when her father-in-law Malhar Rao refused to let it happen.

Singing the Blues:
Taking Down an Insider Threat

"I had all of the advantages. I was already inside the network. No one suspected me. But they found my hack, kicked me off the network...

...and physically hunted me down."

Many pentests start from the outside, wanting to see how the perimeter might be breached.

This pentest started from the inside. My client wanted to assume they had already been breached, and, if breached, how far could an attacker go.

Could they stop me once I was inside?

So they snuck me in. Disguised me as a new employee. Gave me a work computer, an ID badge, an account in their system... hell, I even had a cubicle w/my assumed name on it.

The only person who knew who I really was was their CISO. Everyone else thought I was Jeremy in Marketing.

During most of the first morning, I completed onboarding, made introductions, and completed menial tasks.

But I had to act quick. I only had a week onsite. I had to hack their network while not raising suspicion.

So I set about it.

You have to understand... most "Internal Pentests" are straight forward. The hard part is breaching the network, but once you're inside, it's a target rich environment. End of Life computers, default passwords, everyone a Local Administrator...

Thread about Shashanka and alleged persecution of the Buddhists. The purpose of this thread is to defy their claims while tackling a few other issues.

(Very long thread but useful) 1/n

Shashanka was a Shaivite king of Gauda with his capital being Karnasuvarna.
He is often accused to be a persecutor of Buddhists by the certain historians prejudiced folks to form a picture that Hindu kings were also against other religions just like the muslim kings. 2/n

Much of Shashanka's life after 619 CE is not very much known to us. Historians primarily cite from a few sources like 1) Banabhatta's Harshacharita and 2) Hsuan Tsung's Si Yu Ki(SYK), both being 7th century texts and 3/n

3) Manjushri Mula Kalpa(MMK), an 8th century text sometimes also dated as a 12th century text. 4/n

The method of accusing Shashanka as a Buddhist hater is established by saying that Shashanka desecrated Buddha's sacred marks, destroyed the Bodhi Tree in Gaya and replaced the Buddha statue w Shiva after which he died as he incurred a mortal flesh-rotting disease 5/n

1/ new essay: What's next for marketplace startups? Reinventing the $10 trillion service economy, that's what. Co-authored with @ljin18 https://t.co/fgKbrHTnH5. A short thread 👇

2/ Marketplace startups have done incredibly well over the first few decades of the internet, reinventing the way we shop for goods, but have been less successful services. It's bc services are complex, subjective, fragmented, and often in real life. Makes it hard

3/ There's been 4 major eras at making the service economy work online. The Listings Era, the unbundled Craiglist era, the Uber for X era, and the Managed Marketplace era

4/ Each era has added more value than the last, and utilized technology innovations, from internet to social / "read/write web" to mobile. The "Unbundling Craigslist" era was particularly epic at generating startup ideas

5/ The problem is, all the low-hanging fruit has been picked off. The techniques that got us to here won't get us to the next phase. So we have to do some pretty different things. That's why "Managed Marketplaces" have been a big deal - hire folks as W-2s, certify quality, etc.