BC SCIENCE
Saved by @jay_millerjay

It was great to talk about reproducible workflows for @riotscienceclub @riotscience_wlv. You can watch the recording below, but if you don't want to listen to me talk for 40 minutes, I thought I would summarise my talk in a thread:

 My inspiration was making open science accessible. I wanted to outline the mistakes I've made along the way so people would feel empowered to give it a go. Increased accountability is seen as a barrier to adopting open science practices as an ECR https://t.co/bNK6poNpzx
It also comes across as all or nothing. You are either fully open science or your research won't get anywhere. However, that can be quite intimidating, so I wanted to emphasise this incremental approach to adapting your workflow https://t.co/HS3dx5qJL3
There are two sides to why you should work towards reproducibility. The first is communal. It's going to help the field if you or someone else can reproduce your whole pipeline.
There is also the selfish element of it's just going to help you do your work. If you can't remember what your work means after a lunch break, you're not going to remember months or years down the line https://t.co/iRSXISI5NE
Pre-registration is super helpful, but it takes time to learn how to do it effectively. I had no support for my first attempt and it was awful. https://t.co/o0QgrtBFfJ
But I learnt from my mistakes and eventually got to a point where I'm happy with my approach.
Some aspects of open science can't be added at the end. If you want to share your data, it has to be planned from the ethics stage and your participants have to consent to it. Just remember not all data can be shared openly for ethical reasons.
Sharing materials is one of the easiest things you can do, but very few researchers do it. You can share your stimuli (providing there's no copyright issues) and your task scripts. If you use @GorillaPsyc, there is an open materials function making it super easy.
Double check your analysis pipeline, especially when the results support your hypotheses. I caught an error in my first PhD study before it was too late, but it could have been super embarrassing.
You don't have to go the full R Markdown manuscript route, but I recommend at least scripting any data processing. If you do make a mistake, at least that error is reproducible. You can also use intermediaries like @tidystats to embed results from R into your Word file.
Finally, if you can't read the article in the first place, you can't reproduce it. Most journals allow you to post pre/post-prints and you can upload your dissertation/thesis to Thesis commons. Just double check it's permitted by your target journal: https://t.co/iIIw1VDHdC
Hopefully, this seminar shows people fuck up from time to time. It's about learning from those mistakes and doing what you can to minimise them in future. Try making your workflow more reproducible one step at a time. It'll be worth it in the long-run for you and the community.

More from Science

The Tycoon Mindset
The Tycoon Mindset
@tycoonmindset05
Solara Active Pharma Science con call was today at 3:30 PM.

@Gautam__Baid @unseenvalue @drprashantmish6 @rdkriplani

Here are the key takeaways of the call. 👇🧵

Business Updates:

• Speed of filing products has been increased. Filed 5 new DMFs – 3 in US and 2 in EU
• Currently ramping up the facility in VIZAG with strong customer attraction, and will be commercialized as planned in Q3
• VIZAG EBIDTA growth guidance changed to 40%+ YoY

• Growth Driver: Broad based growth in other products and Vizag.

• PLI: Company has filed Mysore for PLI scheme for 1 molecule.

• Technology: Company is about to complete its 2 out of 3 technology, which will enhance efficiency for Solara.

Demand in some of sectors is moderated:
• Mgmt expected moderation in demand, hence company has taken necessary steps for those products.

Gross Margins:
• It was down a bit due to product mix however.

Fiscal 2022:
• Solara has grown in regulated market space.
• Vizag will kick in. CRAMS will support tailwind.
• Most of the CRAMS is commercial API.

• Most of the product is expected to be stable both in term of demand and price in the coming few quarter
SCIENCE
Lior Pachter
Lior Pachter
@lpachter
"The new answer to a 77-year-old problem"

😭


https://t.co/hm9NoaU4nr


https://t.co/8fKDiKjSWc


https://t.co/jkaicC1F2x


https://t.co/PpxWT4Jef4
SCIENCE
Advertisement
Dr Amanda Moehring
Dr Amanda Moehring
@FlyBehaviour
In Academia, people aren’t always supported when they need it. I want to share what @WesternU did when my husband died right after the pandemic shutdown. It should be shared with other uni’s as a model for empathy and proactive care when someone is in crisis.
1/
#AcademicChatter
SCIENCE
Judy Melinek M.D.
Judy Melinek M.D.
@drjudymelinek
Cognitive Bias in Forensic Pathology Decisions was published today by Journal of Forensic Sciences

From the abstract “We examined all death certificates issued during a 10-year period in the State of Nevada in the United States for children under the age of six.” /2

We also conducted an experiment with 133 forensic pathologists in which we tested whether knowledge of irrelevant non-medical information that should have no bearing on fo- rensic pathologists’ decisions influenced their manner of death determinations. /3

The dataset of death certificates indicated that forensic pathologists were more likely to rule "homicide" rather than "accident" for deaths of Black children relative to White children. /4

“Participants read a vignette describing a not straightforward or simple case in which a 3.5-year-old child was presented to an ED with diminished vital signs and who died shortly after arrival. /5
SCIENCE
JS Oakie\U0001f4dcProtect the 4th Amendment.
JS Oakie📜Protect the 4...
@OakieJs
I think we have to expand our thinking about the toroidal sphere even more. When looking at maps, I noticed the da Vinci map, from 1514, which uses the Reuleaux Triangle. This triangle is formed from 3 intersecting circles, and is in the center of a trefoil.


The trefoil is the focal point in many gothic structures, repeatedly and prominently shown. It is represented in many ways. ‘Going down the rabbit hole’ now makes sense, if you understand the center point of the ears is the center of the torus, with the rabbit trefoil.


The trefoil can be found within the toroidal field. Here is a fun site, where you can manipulate it yourself. https://t.co/FCMcybuuFC


The wiki page makes it seem like there isn’t much of importance with the Reuleaux Triangle, besides being used for coinage, or some stupid bike. But the Wankel engine is an interesting engine, using this geometric design https://t.co/ayPOgkAqGN


https://t.co/m9EaWwF796
SCIENCE

You May Also Like

Angad Singh
Angad Singh
@Singh7575
𝙎𝙝𝙖𝙧𝙞𝙣𝙜 𝙢𝙮 𝙬𝙞𝙨𝙙𝙤𝙢 𝑾𝒐𝒏'𝒕 𝒃𝒆 𝒔𝒖𝒓𝒑𝒓𝒊𝒔𝒆𝒅 𝒊𝒇 𝒕𝒐𝒎𝒐𝒓𝒓𝒐𝒘 𝒖 𝒓𝒆𝒂𝒅 𝒕𝒉𝒆 𝒔𝒂𝒎𝒆 𝒔𝒕𝒖𝒇𝒇 𝒊𝒏 50𝒌 𝒘𝒐𝒓𝒌𝒔𝒉𝒐𝒑 𝒐𝒓 𝒔𝒐𝒎𝒆𝒐𝒏𝒆 𝒎𝒂𝒏𝒂𝒈𝒊𝒏𝒈 𝒚𝒐𝒖𝒓 𝒎𝒐𝒏𝒆𝒚 𝒘𝒊𝒕𝒉 𝒔𝒂𝒎𝒆 𝒍𝒐𝒈𝒊𝒄
Simple and effective way 2 make Money


Idea 1:- Use pivot level like 14800 in case of nifty and sell 14800straddle monthly expiry (365+335) exit if nifty closes on daily basis below S1 or above R1

After closing below S1 if it closes above S1 next day or any day enter the same position again vice versa for R1

Idea2:- Use R1 and S1 corresponding strikes multiple
Incase of R1 15337 take 15300ce
N in case of S1 14221 use 14200pe
Sell both and hold till expiry or exit if nifty closes below S1 or above R1 around closing
If the same bounces above S1 and falls below R1 re-enfer same strikes

Use same criteria for nifty, usdinr and banknifty

(This is must)Use this margin rule for 1lot banknifty pair keep 4Lax margin
For nifty one lot keep 3Lax
For usdinr 100lots keep 4Lax

I bet you if you do this on consistent basis your ROI will be more than 70% on yearly basis.

Couldn't explain easier than this

Criticisms are most welcomed.
OPTIONSLEARNINGS , MONTHLY OPTIONS SELLING , OPTIONS LEARNING
Raman Shalupau
Raman Shalupau
@ksaitor
Maker movement is doing to startups what startups did to corporations.

Here is why 👇

Startups fixed the problem of innovation, that corporations lack.

In big, slow corporations, innovation is a RISK and distraction from the core $$$ profitable business.

Agile startups could launch, iterate fast and eventually stumble upon new growing market opportunities.

However,

When a startup reaches product-market-fit, it has to 🚀 "grow at all costs" and reach market dominance before some giant corporation can replicate their new product and distribute it to their existing giant customer base.

Startup's "growth at all costs" often means growth at the expense of charging customers $$$ money.

Hence, to be sustainable, startups have to constantly chase investor money.

Startup teams spend more time finding and pleasing investors, than finding and pleasing customers.

95% of startups die because they run out of (investor) money + no business model + crazy investor expectations.

Same way corporations die, when unable to adjust to new technology and market shifts.
MAKERS
Advertisement
Jonathan Ware
Jonathan Ware
@ReassessHistory
Rhino Barges

One of the dullest, coolest, more bizarre and fascinating pieces of kit used in Normandy.

Which NO ONE REALLY CARES ABOUT.

BUT I DO AND YOU SHOULD TOO.
/1

#WW2 #SWW #History


Planning for Overlord and Neptune had a serious snag, how to get troops from LSTs onto the beach as simply ramming them onto the beaches and dropping the ramp was known to damage the exceptionally vulnerable LSTs and felt to be unsustainable in the mid to long term. /2


LSTs were essential in sustaining Overlord's progress and were a subject of major headaches in the planning phase, and a real subject of friction when it came to launching additional amphibious operations such as Dragoon.

A single LSTs loss represented a capability nick. /3


So, logic dictated, we don't really want these remarkable but rare and highly valuable vessels constantly doing beach landings, we want something to act as a medium between ship to shore, and in came the (mostly) American designed Rhino. /4


I fucking love Rhinos.

Seriously.

Graceful lines of pure industrial pedigree.

Modular.

LOOK AT IT. /5
HISTORY
Bartosz Ziembinski
Bartosz Ziembinski
@zmbnski
Still wondering about this 🤔


save as q
Q
Delilah S. Dawson
Delilah S. Dawson
@DelilahSDawson
Hello, writers! How about a thread on LITERARY AGENTS? How to get one, how to talk to one, how to keep one happy. Spoiler alert: I am 100% pro agent and can't imagine not having one on my side. 1/

Why would you want a literary agent?
* you want to be traditionally published
* you want someone experienced to help guide your career
* you want to learn how to edit like a pro
* you want to sell foreign and movie rights
* you want answers to your newbie questions 2/

Why you might *NOT* want a literary agent:
* you want to self publish
* you're not willing to compromise on your edits
* you don't think their expertise is worth 15% of your advance
I... can't think this way. Literary agents have been crucial to my career. 3/

So, how do you get a literary agent?
1. Have a finished, revised, edited, polished manuscript.
2. Write a query letter for your book
3. Send your query to agents who rep your genre and are open to submissions
4. Repeat steps 1-4 until you're offered representation. 4/

So, let's go through those four steps. First of all, you must have a finished, revised, edited, polished book, and it must be sellable. That is, you can't sell a 600k picture book or a 40k adult Fantasy, etc. You must read extensively in the genre you're writing. 5/
WRITING