So much has happened this year – the global pandemic, of course, but also political chaos, freak weather and wildfires, and protests everywhere.

So how do we capture 2020? @ReutersGraphics stitched together clippings from the longest year 👇 https://t.co/83ZgiqzV0W 1/13

January
🦠 The world welcomed 2020 as wildfires and protests clouded celebrations. Cities close to Wuhan saw a rise in coronavirus cases 2/13
February
The first coronavirus-related death occurred outside China.

⚽ One of the last soccer matches was played with fans in the stadium. One month later, Valencia said 35% of the squad tested positive for the virus 3/13
March
A deluge of death in northern Italy; Poor Indians flee to villages

’Some people will die of the virus. The rest of us will die of hunger,’ said Sanjay Sharma, a Mumbai taxi driver 4/13
April
China’s Wuhan came out of lockdown; A bread making frenzy swept the UK 🍞

Spain lifted its lockdown for children. Below, Paolo drew himself in a farm.
He said he missed climbing, friends and his grandparents the most 5/13
May
📈 Unemployment skyrocketed globally.

‘It took a month of pandemic to lose it all,’ said Douglas Felipe Alves Nascimento, who lost his job in Sao Paulo, Brazil.

Brazil jumped to having the second highest number of cases globally 6/13
June
Millions took to the streets globally to embrace the #BlackLivesMatter movement.

📚 A historic Oakland Black book store sold out of books on racial discrimination 7/13
July
🏅 The Tokyo Olympics were postponed and the world of sports adapted.

England allowed pubs, restaurants and hair salons to reopen 8/13
August
The WHO asked people to stop partying; Nintendo profits skyrocketed thanks to @animalcrossing; Thousands protested in Berlin against masks 9/13
September
The second waves arrived. Thai protesters challenged the monarchy at the biggest demonstration in years. Read our @specialreports: https://t.co/tmOFMEFgd4 10/13
October
Trump and Melania tested positive for the virus as Americans headed to the polls.

🇮🇳 Festivals continued in India with the help of disinfectant and essential workers 11/13
November
Vaccine trials offered a glimmer of hope … and then the world mourned soccer star Maradona 12/13
December
💉 Vaccines arrive, with Britain expecting to receive millions by year-end.

More than 1.6 million people have died from COVID-19 around the world.

See more from a year filled with sorrow https://t.co/gZqo3O2fJq 13/13

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You want to know about Barockschloss Ludwigsburg? Too bad, I'm going to tell you some stuff about it, as it's my 'local'...


It all came about because Eberhard Ludwig, Duke of Württe.berg, decided in 1704 that he wanted a big old palace from which to be an absolutist Duke, and do absolutist things. So, picking an old hunting lodge, he started to extend it...


Thing is, though, to build a residential palace, you need a workforce. To gain a workforce, they needed somewhere to live. So, alongside the palace, he founded the town of Ludwigsburg, now adjacent to Stuttgart.


Ludwig resided at Ludwigsburg until 1733, when, childless, he kicked the bucket. Then Carl-Eugen, a relative, became Duke, and that's when things became lit.


See Carl Eugen had been raised in the court of Frederick the Great, and had been deprived of fun and female company - they were banned from the Prussian court.

So, he was essentially a big fat party animal from the get-go.
A quick thread on the new variant, pulling together information from news sources, twitter, genomic databases, and word from well-placed peers.


The new variant in the UK consists of several mutations in the spike protein, including ΔH69/ΔV70 deletions & other receptor binding domain mutations such as N501Y.

The variant is described here in this pre-print from @GuptaR_lab.

https://t.co/ui2U1r1ANA


The ΔH69/ΔV70 variant continues to increase quite rapidly as a proportion of overall positives (roughly doubling in the last 2 to three days), and is apparently now the dominant strain in test positives in some regions.

Extensive efforts have gone into enhanced surveillance for the ΔH69/ΔV70 deletion with and without RBD mutations, and it is good that we are aware of this.

There is a need for calm and rational thinking, and more evidence is needed.

But the early data is certainly concerning

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