A quick thread on the new variant, pulling together information from news sources, twitter, genomic databases, and word from well-placed peers.

The new variant in the UK consists of several mutations in the spike protein, including ΔH69/ΔV70 deletions & other receptor binding domain mutations such as N501Y.

The variant is described here in this pre-print from @GuptaR_lab.

https://t.co/ui2U1r1ANA
The ΔH69/ΔV70 variant continues to increase quite rapidly as a proportion of overall positives (roughly doubling in the last 2 to three days), and is apparently now the dominant strain in test positives in some regions.
Extensive efforts have gone into enhanced surveillance for the ΔH69/ΔV70 deletion with and without RBD mutations, and it is good that we are aware of this.

There is a need for calm and rational thinking, and more evidence is needed.

But the early data is certainly concerning

More from News

.@louiscasiano from @FoxNews reached out to ask if we are actually planning on contaminating the hotel rooms of Proud Boys with bedbugs. The short answer is no, we don't even know if that's possible. But here's our full response.


That post was clearly satire. We have no idea how one would actually go about the activity that was suggested.

What is not satire are the numerous death threats that were sent to us by Trump supporters in the lead up to the November election.

Here are a few tweets depicting detailed and credible death threats that you didn’t ask for comment on:
https://t.co/UiI12M0Aey.
https://t.co/PPe75XWImX
https://t.co/4Ia8659wK8
https://t.co/n5ov6R8Gyh


Each of those tweets includes the email address of the sender. We wish you luck in reaching out to them for comment.

Further, the hate crimes committed by the Proud Boys during their last visit to DC were not satire. A marauding band of drunk white nationalists stormed through our city, tearing down and burning religious symbols declaring respect for Black lives.

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Trump is gonna let the Mueller investigation end all on it's own. It's obvious. All the hysteria of the past 2 weeks about his supposed impending firing of Mueller was a distraction. He was never going to fire Mueller and he's not going to


Mueller's officially end his investigation all on his own and he's gonna say he found no evidence of Trump campaign/Russian collusion during the 2016 election.

Democrats & DNC Media are going to LITERALLY have nothing coherent to say in response to that.

Mueller's team was 100% partisan.

That's why it's brilliant. NOBODY will be able to claim this team of partisan Democrats didn't go the EXTRA 20 MILES looking for ANY evidence they could find of Trump campaign/Russian collusion during the 2016 election

They looked high.

They looked low.

They looked underneath every rock, behind every tree, into every bush.

And they found...NOTHING.

Those saying Mueller will file obstruction charges against Trump: laughable.

What documents did Trump tell the Mueller team it couldn't have? What witnesses were withheld and never interviewed?

THERE WEREN'T ANY.

Mueller got full 100% cooperation as the record will show.