@NCPV @Micro_MDPI Can you comment on Professor Gallaher's statement concerning the possibility of SARS-COV-2 recombining with

@Pirbright_Inst @NCPV @Micro_MDPI Gallaher's "Prophecy" Is it Likely?
MERS + SARS-COV-2 Combo Event
MERS Situation Update - January 2020
https://t.co/K2AB0fTpJT
SA Cases:
https://t.co/ix083ozN0v
UAE Cases:
https://t.co/eCBVg3oSPo
@Pirbright_Inst @NCPV @Micro_MDPI 1. "Specificity of S is largely responsible for widespread & rapid communicability of SARS-CoV-2, with relatively low virulence in most infected; in contrast, spread of MERS is more easily contained, but its virulence is much higher, at 35%."
@Pirbright_Inst @NCPV @Micro_MDPI 2. A virus with high communicability of SARS-CoV-2 & the virulence of MERS would be apocalyptic in its impact!
There is a breakpoint sequence in MERS S (25215CAGAT) that is similarly very close in relative position to 25047CAGAT in SARS-CoV-2.....
@Pirbright_Inst @NCPV @Micro_MDPI 3. There is a 4th breakpoint sequence, between the receptor binding domain of MERS & the S1/S2 junction, that is precisely conserved in sequence & position with the corresponding location of SARS-CoV-2:
23577CAGAC in MERS
23300CAGAC in SARS-CoV-2
@Pirbright_Inst @NCPV @Micro_MDPI 4. This breakpoint, is identical in both viruses at the same relative position in the S1 protein sequence, where it defines an identical dipeptide, QT
(see underlined section in the PDF)
https://t.co/Glh98zcbWP
@Pirbright_Inst @NCPV @Micro_MDPI 5. There is potential, based on closely apposed or identical breakpoint sequences, that the bulk of the S1A and S1B domains of the S1 attachemnt subunit could be exchanged between MERS and SARS-CoV-2 in any mixed infection.
@Pirbright_Inst @NCPV @Micro_MDPI 6. While there is no indication that this has occurred in the wild, during the SARS-CoV-2 pandemic we face the unique situation of SARS-CoV-2 being present simultaneously in a substantial number of human beings worldwide.
@Pirbright_Inst @NCPV @Micro_MDPI 7. Simultaneous outbreaks of MERS, within or without areas where it has been found prevalent, could produce mixed infections in humans that we know have resulted in frequent recombination among Covs in the wild or in captive populations of animals.
@Pirbright_Inst @NCPV @Micro_MDPI 8. To the viruses, there is no known theoretical difference!
"Public health authorities should especially guard against simultaneous spread of more than one coronavirus in the human population at the same time & location"
https://t.co/O2CHJQVCXP

More from Billy Bostickson 🏴👁&👁 🆓

PCR Drosten Fail Compilation
1. Ten Fatal Errors: Scientists Attack Paper That Established Global PCR Driven Lockdown
https://t.co/25p88F2xu6
2. Review report Corman-Drosten et al.
https://t.co/8rlT4MWoyI
3. Consequences of false

PCR Drosten Fail Compilation
4. Files for download
https://t.co/SqDrZjB9em
5. Addendum
https://t.co/IygCWvnAsP
6. False positives in reverse transcription PCR testing for SARS-CoV-2
https://t.co/HxpSZkzZ7Q
7. Discussion on Retraction

PCR Drosten Fail Compilation
8. 124 Tweet Thread by Bobby Rajesh Malhotra
@Bobby_Network
https://t.co/cdot5yIeuf
9. Another shorter thread by @Bobby_Network
https://t.co/kqFW9GsSeD
10. Thread by Abir Ballan

PCR Drosten Fail Compilation
11. Mini Thread by @Kevin_McKernan
https://t.co/pntydnd80L
12. Another longer thread by @Kevin_McKernan
https://t.co/5hBYIlXFnQ
13.
1. Thread: RaTG13 Real or Fake?
A Norwegian Scientist @Vehuardo recently claimed RaTG13 is an "authentic virus"
https://t.co/tAXMNTwdhA
This failed to take into account the work of our DRASTIC colleagues & other published analyses.
This thread is a polite attempt to educate.

2.
https://t.co/tw606vgHwp
which says RaTG13 doesn't make sense on how it was sequenced, or how the data got so messed up in the lab as to include copy paste mistakes, bat dna, pangolin dna, rice dna, mice dna, & nobody should use it to form conclusions until it's properly vetted

2 (cont)
"sequence is incomplete & provided segment doesn't function. The identified markers suggest partial match basis & actual virus itself as described by the sequence can't functionally exist due to incoherent structures that appear to be the result of sample contamination"


3. RaTG13 integrity is further attacked here:
The Validity of critical pieces of evidence for the natural origin of SARS-CoV-2 is Dubious, and needed to be

4. and here:
Major Concerns on the Identification of Bat Coronavirus Strain RaTG13 and Quality of Related Nature
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
2 papers:
Human–viral molecular mimicry
https://t.co/irfH0Zgrve
Molecular Mimicry
https://t.co/yLQoUtfS6s

2. Must Read! Confirmation with supporting evidence via @flavinkins
https://t.co/NEf9HK6ReB
"ONLY place where this thing could emerge, naturally or Artificially, is by passage in HUMANIZED MICE"

3. Springer Article


4. Takeaway most significant quotes from Springer Article, burn this into your brain:
"Such a peptide commonality is unexpected and highly improbable from a mathematical point of view"


5. One image to explain it all!

More from Life

This month I’m turning 22.

To celebrate, here are the 22 best threads I’ve found on Twitter this year.

Mostly about:

•Life/purpose
•Startups
•Entrepreneurs
•Writing
•Clarity of thought

If I see more interesting threads, I will add to this list.

Enjoy!

1. @ryanstephens: Need tips on growing a newsletter, mastering Twitter, writing online?

@ryanstephens breaks down a podcast discussion between @davidperell and @nathanbarry

Here’s what you can


2. @jackbutcher: How to separate your time from your income

•Explore the market
•Build equity
•Build products and services
•Scale your reputation
•Break the matrix

A fantastic thread complete with helpful


3. @AlexAndBooks_: I love to read.

Here is a great thread on 10 fantastic books.

Includes a short summary of each.

Don’t just take it from me, this is straight from the legend: @AlexAndBooks_


4. @m_franceschetti My biggest revelation in 2020 was the importance of sleep.

Here, @m_franceschetti founder of @eightsleep gives us his eight sleep hacks to improve sleep for 2021.

Do these and your productivity will

You May Also Like