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Definitely not the first to post on this but am completely floored by a 2008 paper published in the Journal of Infectious Diseases by Professor David Morens (Medical Epidemiologist), Dr Jeffery Taubenberger (Virologist), and Dr Anthony Fauci (Immunologist) at the NIAID. 1/11

 In the paper the authors question the cause of mortality during the 1918 pandemic and those which follow. They go on to hypothesize and prove that bacterial pneumonia is actually the prominent causative factor during viral respiratory pandemics. 2/11
Part of the methodology was examining several histological specimens which had been preserved from the pandemic. They found that in essentially every single case there was evidence of severe acute bacterial pneumonia either as predominant or in conjunction with virus. 3/11
The paper notes that previous post mortem cultures picked up bacterial colonization with more than half of those being pathognomonic. 4/11
Morens et al. note that subsequent pandemic deaths were also attributable to secondary bacterial pneumonia following primary viral infection despite significant advancements in medicine. 5/11
The paper concludes that ample evidence from influenza pandemics (and similar viruses) spanning almost a century indicates that viral deaths are actually due to bacterial infection. 6/11
The authors even provide a solid explanation for why we might be masking bacterial pneumonia deaths in this context, and note that primary viral pneumonia deaths are exceptionally rare “even in pandemic peaks”. 7/11
There’s then this throw forward to the “next pandemic” in which the authors note that a human-adapted virus (Influenza; SARS-CoV-2) will cause severe disease by bacterial colonization in the background of viral infection. 8/11
The paper was published in 2008 by 3 leading scientists at least one of whom now seems to have forgotten he ever wrote this. It’s available for viewing and download here:

https://t.co/urpWqLFpij

9/11
If we knew in 2008 that co-infection during respiratory pandemics is the major driver of mortality, then why are we basically ignoring this entirely in 2020?

New variant and less than perfect vaccine, or bacterial infection we’re not treating properly for viral obsession? 10/11
There are so many questions to be asked given the existence of this paper and the people who published it. We are treating pandemic science as if it started in March of this year when in fact we have lots of good data prior to this - if only we’d read it. 11/11

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Roland Baker
@RolandBakerIII
Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD. This is a plain English Description of the code:
https://t.co/w7koHyMJjL

The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation

Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage


An overview of the encoded spike


Initial mouse
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Defense News Nigeria
Defense News Nigeria
@DefenseNigeria
The people can always be brought to the bidding...tell them they are being attacked, and denounce the naysayers for lack of patriotism and exposing the country to danger.

Hermann Goring

We've seen reports of Yoruba leaders asking President Buhari to stop the war and sack service chiefs immediately as a way of beginning restructuring.Our country is sitting on a keg of gunpowder they claim. Once again partisan hacks want to snatch victory from the jaws of defeat.

You see, when you are fighting small limited wars there is a natural inclination , on the part of politicians not directly impacted by the war to want to blow things out of proportion. There is a basic disconnection now in this country between the population and the war

....and i find it quite frankly. Frightening. Compared to what was obtainable 2015, the security situation in Nigeria has vastly improved yet the media ..and partisan hacks portray a much more pessimistic narrative.

Consider that in 2015 over 21 Local government areas and 2.6 million Nigerians were cut off from the rest of the country, under the administration of a caliphate in Nigeria for 16 months. A huge chunk of the northeast was no mans country.
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Simon Wardley
Simon Wardley
@swardley
X : Do you think cloud will decentralise?
Me : Already has - started with regions and AZs and is now rapidly expanding into outpost, greengrass, EKS anwhere.
X : No, I mean many providers.
Me : There are two forms of decentralisation - provision and control (i.e. authorities) ...

... what is happening is decentralisation of provision (i.e. cloud everywhere, at the edge) but under centralised authorities (Amazon, Alibaba, MSFT, Google etc).
X : What about decentralisation of control?
Me : Many companies working to a common standard ...

... that was the dream of OpenStack but they blew that on day one creating a collective prisoner dilemma. They are trying to recorrect this with K8s but the cloud has moved on, higher up the stack ...

... so, the idea of a marketplace of many different companies each having authority is ... wishful thinking by past vendors and clients they've hoodwinked. Maybe in 15-20 years we will get another go ... open source is a long game ...

... more likely is many points of provision i.e. companies offering EKS anywhere on a utility basis but under centralised authority e.g. AWS.

So, yes, the cloud is going to edge, has been for sometime but it'll be AWS / Alibaba / MSFT cloud that is everywhere.
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Elbridge Colby
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@ElbridgeColby
There is some valuable analysis in this report, but on the defense front this report is deeply flawed. There are other sections of value in report but, candidly, I don't think it helps us think through critical question of Taiwan defense issues in clear & well-grounded way. 1/


Normally as it might seem churlish to be so critical, but @cfr is so high-profile & the co-authors so distinguished I think it’s key to be clear. If not, people - including in Beijing - could get the wrong idea & this report could do real harm if influential on defense issues. 2/

BLUF: The defense discussion in this report does not engage at the depth needed to add to this critical debate. Accordingly conclusions in report are ill-founded - & in key parts harmful/misleading, esp that US shldnt be prepared defend Taiwan directly (alongside own efforts). 3/

The root of the problem is that report doesn't engage w the real debate on TWN defense issues or, frankly, the facts as knowable in public. Perhaps the most direct proof of this: The citations. There is nothing in the citations to @DeptofDefense China Military Power Report...4/

Nor to vast majority of leading informed sources on this like Ochmanek, the @RANDCorporation Scorecard, @CNAS, etc. This is esp salient b/c co-authors by their own admission have v little insight into contemporary military issues. & both last served in govt in Bush 43. 5/
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Jennifer Abdo
Jennifer Abdo
@J_Abdo
Horseshoe theory sets off my bs detector & the divisions on the left leave me at a loss for an explanation- Venn diagram? Another shape? What's going on?
Enter @bastardspod! They really break this down & sort it out in a way that helped me out a lot.

Three of their points I found particularly useful in explaining why the horseshoe looks correct to some or why/how some ppl that look left-ish are really extreme right or take that turn (ally with boogaloo or proud boys, for instance?). 2/10

📍as you go farther left, some are more attracted to authoritarianism or violence like those on the right. BUT this is NOT a horseshoe bc the ideals of left & right are starkly different. That's important - this isn't a horseshoe. 3/10

Their examples are Kessler (of Unite the Right) who started in Occupy Wall St NY & Mussolini who started out against imperialism. Seemingly left-ish ppl turned fascist - why? I agree with the hosts when they said if you're anti-authoritarian, you won't end up a fascist. 4/10

📍(surprise!) toxic masculinity (they don't use those words) or wounded masculine pride is a factor. The pod says~getting the shit kicked out of you can push men in a violent authoritarian direction. Feeling disenfranchised like MRAs and white nationalists seems related too. 5/10
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@FionaPearman @ScottMorrisonMP Morrison is our statue of unempathic neoliberalism - erected by evangelical and corporate Australia to celebrate their victory over compassion, equality and secular humanism. 

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Pran Katariya
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The Straddle is my favorite trade these days. But more often than not, one needs to adjust to make a good return from it. There are many ways to do this depending on your view, psychology and imagination. Will discuss a few that I use

The Straddle is a delta neutral strategy and it is important to keep deltas in check during the course of the Trade and not let them run away from you. Of course Volatility is the elephant in the room- but not going there as that will require a separate discussion

The first and most common method is to go 'inverted.' That is to say to shift the untested side to generate additional Premium and increase the runway to Breakeven. So if you start with a Straddle at 700 and price goes to 740, you can move the PE up to say 720.

How much should you move the untested side? While again this is a matter of skill, experience and artistry, the rule of thumb is to cut deltas by half. Remember, prices will move and you have to allow sufficient room for them to fluctuate

The second method is to shift the entire Straddle in the direction of the move. So if you have a 700 Straddle and Price goes to 740, you can shift the Straddle to 720. If you time this right, it can generally be done at virtually no cost or minimal cost.
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itrade(DJ)
itrade(DJ)
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Here is the detailed information of about strategy,

Entry time : 9.30 - 10
Exit : Upto you

Strategy :
Sell weekly ATM CE & PE at almost equal price
For ex : Sell Nifty 17250 CE at 50 and Nifty 17250 PE at 48 so it will become short straddle

Buy monthly ATM or near ATM CE & PE at matching price (5-10 points diff should be fine) as hedge
For ex : Buy Nifty 17250 CE at 150 and Nifty 17300 PE at 155 so it will become long straddle.

Weekly Short straddle + Monthly Long straddle

Adjustment:

• If you feel slightly bullish/bearish then no adjustment needed
• If Nifty moves 50 up or down and sustain then just simply roll up or down half of qnty and keep rest of the quantity. If market goes up or down further then roll up or down rest.

• If Nifty moves one side or about to breach BEP then add equal amount of lot. This can balance tested side. For ex: If I bought 17300 CE 4 lot as hedge then add 4 lot so you will have only one side risk . Note: Remember to keep SL at cost price (only for additional lot bought)

Capital requirement:
2.2 L for 4 lot
Adjustment requires additional capital upto 1L

Note : High risk high reward strategy, please don’t execute until you fully understand. Kindly do paper trading or backtest.
RR : 1:1
POP : 45-55%
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Anshul Pandey
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BRAHMA VAIVARTA PURAN: IMPORTANCE AND CHARACTERISTICS.

This Puran introduces us to way of Vedas. On the request of Narad Muni Bhagwan Saavarni had preached this Puran. It is a summary of Dharma, Arth, Moksha etc.


Listening to this Puran one gets automatically attached to Vishnu and Shiva and realize that there is no difference between them. Vyasji divided this book into four parts. It has eighteen thousand shlokas. This whole book is in the form of dialogue between Suutji and Maharishi's.

The first part Brahmkhand, consists of Shrishti description. Here Shri is known as Para Brahma and description of Gokul is also mentioned, It also narrates the argument between Brahma and Narad in which both were defeated, and then Narad went to Shiva to attain more gyan.

Shivji advised him to go to Bhagwan Saavarni for this. Narad goes to Saavarni ashram to seek Knowledge and is totally amazed by the sorroundings.

Next is Prakriti khand which consists of dialogue between Narad and Saavarni where they discuss the

Importance of Shri Krishna through various stories. Then there is the discussion of Prakriti and its various hues. Listening to this gets you wealth.
Next is Ganesh Khand which describes the Punyak vrat done by Parvati ji. After this it narrates the birth of Kartikeya and Ganesh.
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\u0936\u094d\u0930\u0940\u092e\u093e\u0932\u0940 \u0939\u093f\u0924\u0947\u0936 \u0905\u0935\u0938\u094d\u0925\u0940
श्रीमाली हितेश अवस्थी...
@HiteshAwasthi89
Bhu Varaha Swamy Temple

Bhu Varaha Swamy temple is a Hindu temple, located at Srimushnam, in the South Indian state of Tamil Nadu. Constructed in the Dravidian style of architecture...


the temple is dedicated to Varaha (Bhu Varaha Swamy), the boar-avatar of the god Vishnu and his consort Lakshmi as Ambujavalli Thayar.

The temple had contributions from Medieval Cholas of the 10th century with later expansions by Thanjavur Nayak king Achuthappa Nayak.


A granite wall surrounds the temple, enclosing all the shrines and the temple tanks. There is a seven-tieredrajagopuram, the temple’s gateway tower.

Six daily rituals and three yearly festivals are held at the temple, of which the Chariot festival....


celebrated during the Tamil month of Vaikasi (April–May), being the most prominent. The festival also symbolises Hindu-Muslim unity in the region – the flag of the chariot is provided by Muslims; they take offerings from the temple and present to Allah in the mosques.


Source & Pic credit : Anusri
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