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1. Yes, Trump will claim to intend to target GOP senators up for reelection in '22 (like he did to Thune with Kristi Noem) if they don't join in @HawleyMO's sedition on Jan. 6, but the fact is, it's not clear whether Trump will be successful in ANY of those efforts & voting yes


2. to hedge off these threats will also create fissures & fractures for these incumbents among other elements of their party that could complicate their renominations. Indeed, what worries me the most about the potential for the country to slip into @anneapplebaum territory is

3. that what should be robust and intense push back from the party establishment against actually ending democracy- bc that's what Trump's request would do, if it was granted, is fairly muted. What we SHOULD be seeing from the mainstream of the party is threats to strip committee

4. assignments, chairs, privileges, even reelection funds, if anyone gets involved in this bullshit- in the House & the Senate, and the fact that you don't see it is more than a story of McConnell & McCarthy being afraid of Trump & his base. Its a story of receptivity, of the

5. level of receptivity the congressional and party leadership is dealing with both within the rank and file membership of the party and within its donor class, and THAT, my friends, is why you find me so concerned. That, and my decision to finally pull @anneapplebaum's book

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@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)

@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice


@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2


@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj


@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o