https://t.co/Sd9IslUCH5 a FCS need a FCS in the inoculum to exist. It can not arise de-novo as it will be destroyed instantly by the immune system.
https://t.co/PG7LVnHfsy
Even with VERO E6, only half the time does passage lead to the loss of the FCS—smaller plaques need to be explicitly picked for that to be a certainty.
https://t.co/s70jNIvUb4
As for why “55% of the December 2019 cases were connected to the huanan seafood market”? “Contact history to the huanan seafood market” was literally written into the standard for reporting a case as SARS-CoV-2 infection in Wuhan
https://t.co/sqsq5x3YRw
In fact, they were still defending their claim of the seafood market as the absolute index case in Wuhan—they only admit “uncertainty” in the case reporting, while still attempt to defend
2/ Early MERS/CoV-1 spread showed a 50/50 rate of human versus animal transmission; lots of posterior diversity. With CoV-2, 1001 early Chinese genomes show No... ZERO posterior diversity. Flipping 1001 coins & getting heads every time? That's a one in 10 with 84 zeros chance
— Dr Steven Quay (@quay_dr) December 8, 2020
WHO Report:
— Dr Steven Quay (@quay_dr) June 11, 2021
10,000 archived blood samples in Wuhan & no seroconversion
80,000 animals & no CoV-2
1.9 MM viruses in GISAID & no posterior diversity
All c/w lab origin
People keep saying we don't have evidence for the origin of CoV-2@mattwridley @Ayjchan @AlexBerenson #COVID19
A zoonosis, whether community or laboratory acquired, have 3 elements in common: infected animal(s), viruses, and humans.
— Dr Steven Quay (@quay_dr) May 26, 2021
The differences are natural diversity versus a laboratory singularity.
What do the facts say?#COVID19 pic.twitter.com/K2kEAxGsR0
True but following data must be in the prediction: its not the market, not Hubei bats, not Hubei farmed animals, not pangolins, no Wuhan sero+ background as with SARS-1 & MERS, no post. diversity as with MERS, 1st 50 pts <15 km from world's expert on lab made chimeric CoVs
— Dr Steven Quay (@quay_dr) September 20, 2020
Given that the zoonoses, SARS1 and MERS, had >85% positive tests in markets, the likelihood CoV-2 is a zoonosis like SARS1 or MERS is less than 1 in a 1,000,000.
— Dr Steven Quay (@quay_dr) May 27, 2021
1/ A hallmark of a zoonotic epidemic is community undetected infection pre "Patient Zero." This is detected retrospectively with diagnostic tools looking at archived specimens.
— Dr Steven Quay (@quay_dr) November 1, 2020
Example: Of 7461 archived blood specimens from 2011-2016 in Saudi Arabia, 2.3% were positive for MERS
CoV-1 v. CoV-2:
— Dr Steven Quay (@quay_dr) December 12, 2020
CoV-1: 91 civets & 15 raccoon dogs in wet markets tested: 106/106, 100% positive. https://t.co/BKB4F3p7ev
CoV-2: 0 of 336 specimens from wildlife sold at Hunan market are positive for CoV-2. @gdemaneuf 's nice annotation of the WHO ToR https://t.co/k5r5Hnskbm
2/ 1271 nasal swab & 357 matched blood specimens from patients in Shanghai 1 Dec 2018 to 31 Mar 2020 were examined for CoV-2 by PCR. First positive is 25 Jan 2020.
— Dr Steven Quay (@quay_dr) November 1, 2020
This is not c/w a zoonotic epidemic but is consistent with a lab escape origin.https://t.co/fE9WSpeXS4
https://t.co/wDDy1s6Tmk
On SARS-CoV and MERS-CoV: Highly prevalent in Civets, Raccoon dogs in market, as well as in camel herds.
https://t.co/WeI8UOx9R8
On seroprevalence of SARS-CoV and MERS-CoV.
https://t.co/18qKGTXn0y
https://t.co/Xx7GjNOiEc
(And other clades of SARS-CoV-2)
— Daoyu (@Daoyu15) July 21, 2021
Observation 4: All tested ACE2 favors H,Y or F on position 498 over Q498. The only RBD that is better with Q498 is Rs7327. However, it is not relevant to SARS-CoV-2, and carried a F498 by default, indicating that other constraints (folding) is at pic.twitter.com/e1WN3aFoXc
The RdRp had an anomalously high resistance to Remdesivir—best explained by passaging in the presence of RDV/RTP.
Mojiang miners. This is why the oral serological claims made by the WIV can not be trusted in any way. No Data for the Shi addendum, or any of the claimed seronegativity of the WIV workers.
Note that there were 2 genomes in Wuhan and 15 out of the 91 genomes from Sichuan before 2021 carrying intermediate between A and B lineage, with sampling outside the market generally returning much greater diversity than inside the market.
Then, there is an increase in the amt of S seropositivity in sera collected in France in December 23 2019, which would have required the first widespread transmission of SARS-CoV-2 in france beginning at 09/2019--with substantial amt of infection well
Another clue came from italy, which have shown consistent qRT-PCR positivity from wastewater (this is not the november claim with just one sample. this is consistent PR-PCR positivity) since 18/12/2019, which once again
Similarily, consistent detection of SARS-CoV-2 have been reported in Brazil between 27/11/2019 and 11/12/2019. Note that A lineage have been found just south of the location being sampled, and is found in South america in general.
In deed, this would have been consistent with SARS-CoV-2 having a tMRCA in November 17 2019, which is consistent with WIV and WIBP as the origin, with the first outbreak happening in Wuchang, in stead of with the Huanan market as the origin.
In deed, before the more widespread control on the narrative for SARS-CoV-2 origins were established in China, there were reports of contact tracing for first case as early as in 17 November 2019, which is once again earlier than the market, but would have
Considering the extreme censorship of early cases in China, and the existence of consistent
In deed, much higher diversity exist outside of the market than inside the market for the earliest
Certain florida cases also have an onset date at Jan 1 2020.
There are other possible points before, but they are dubious at best. The first confirmed PCR positivity in Italy and Brazil pushes the arrival date of SARS-CoV-2 at these 2 countries (A, possibly A or B) at 27/11/2019.
https://t.co/nUBbhzXisU
Very similarly, this happened as well. as many as 4/5 times the active cases were simply removed (not recognized) before the beginning of 2020, simply because they are not epimediologically linked to the Huanan seafood market--you aren't going to find
More from Daoyu
@JackDempsey2_2 @pathogenetics @ggronvall
@pathogenetics @ggronvall And 100% of all the alleged market animal photos were taken in 2017. https://t.co/Vh4dKy6rvI there is a reason why that animal paper refused to release the per-month data of animal sales in the wet markets—the sales were completely banned in 2018 when the consumption of
@pathogenetics @ggronvall Contraband animals were prohibited in an 2017 revision fo the CCP’s own “wildlife protection law”. This targets the main reason for consumption, which is to brag as a social status. No animals or their meat were ever sold in wet markets or online after that date. The only things
@pathogenetics @ggronvall Ever sold after the date were desiccated and sun-dried parts for use in jewelry and for medicine. They are always thoroughly dried out which would inactivate all enveloped viruses incl. all coronaviruses within them if they were present.
@pathogenetics @ggronvall https://t.co/2679qQiA0P
The claimed market origin is undermined by the presence of consistent positive SARS-CoV-2 detection in wastewater and in patient samples outside China in at least two different countries well into November 2019, which is before the first case in the wet
@pathogenetics @ggronvall And 100% of all the alleged market animal photos were taken in 2017. https://t.co/Vh4dKy6rvI there is a reason why that animal paper refused to release the per-month data of animal sales in the wet markets—the sales were completely banned in 2018 when the consumption of
@pathogenetics @ggronvall Contraband animals were prohibited in an 2017 revision fo the CCP’s own “wildlife protection law”. This targets the main reason for consumption, which is to brag as a social status. No animals or their meat were ever sold in wet markets or online after that date. The only things
@pathogenetics @ggronvall Ever sold after the date were desiccated and sun-dried parts for use in jewelry and for medicine. They are always thoroughly dried out which would inactivate all enveloped viruses incl. all coronaviruses within them if they were present.
@pathogenetics @ggronvall https://t.co/2679qQiA0P
The claimed market origin is undermined by the presence of consistent positive SARS-CoV-2 detection in wastewater and in patient samples outside China in at least two different countries well into November 2019, which is before the first case in the wet
@franciscodeasis https://t.co/OuQaBRFPu7
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the
chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project
starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".
P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!
https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the
chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project
starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".
P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!
https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?
More from All
MASTER THREAD on Short Strangles.
Curated the best tweets from the best traders who are exceptional at managing strangles.
• Positional Strangles
• Intraday Strangles
• Position Sizing
• How to do Adjustments
• Plenty of Examples
• When to avoid
• Exit Criteria
How to sell Strangles in weekly expiry as explained by boss himself. @Mitesh_Engr
• When to sell
• How to do Adjustments
• Exit
Beautiful explanation on positional option selling by @Mitesh_Engr
Sir on how to sell low premium strangles yourself without paying anyone. This is a free mini course in
1st Live example of managing a strangle by Mitesh Sir. @Mitesh_Engr
• Sold Strangles 20% cap used
• Added 20% cap more when in profit
• Booked profitable leg and rolled up
• Kept rolling up profitable leg
• Booked loss in calls
• Sold only
2nd example by @Mitesh_Engr Sir on converting a directional trade into strangles. Option Sellers can use this for consistent profit.
• Identified a reversal and sold puts
• Puts decayed a lot
• When achieved 2% profit through puts then sold
Curated the best tweets from the best traders who are exceptional at managing strangles.
• Positional Strangles
• Intraday Strangles
• Position Sizing
• How to do Adjustments
• Plenty of Examples
• When to avoid
• Exit Criteria
How to sell Strangles in weekly expiry as explained by boss himself. @Mitesh_Engr
• When to sell
• How to do Adjustments
• Exit
1. Let's start option selling learning.
— Mitesh Patel (@Mitesh_Engr) February 10, 2019
Strangle selling. ( I am doing mostly in weekly Bank Nifty)
When to sell? When VIX is below 15
Assume spot is at 27500
Sell 27100 PE & 27900 CE
say premium for both 50-50
If bank nifty will move in narrow range u will get profit from both.
Beautiful explanation on positional option selling by @Mitesh_Engr
Sir on how to sell low premium strangles yourself without paying anyone. This is a free mini course in
Few are selling 20-25 Rs positional option selling course.
— Mitesh Patel (@Mitesh_Engr) November 3, 2019
Nothing big deal in that.
For selling weekly option just identify last week low and high.
Now from that low and high keep 1-1.5% distance from strike.
And sell option on both side.
1/n
1st Live example of managing a strangle by Mitesh Sir. @Mitesh_Engr
• Sold Strangles 20% cap used
• Added 20% cap more when in profit
• Booked profitable leg and rolled up
• Kept rolling up profitable leg
• Booked loss in calls
• Sold only
Sold 29200 put and 30500 call
— Mitesh Patel (@Mitesh_Engr) April 12, 2019
Used 20% capital@44 each
2nd example by @Mitesh_Engr Sir on converting a directional trade into strangles. Option Sellers can use this for consistent profit.
• Identified a reversal and sold puts
• Puts decayed a lot
• When achieved 2% profit through puts then sold
Already giving more than 2% return in a week. Now I will prefer to sell 32500 call at 74 to make it strangle in equal ratio.
— Mitesh Patel (@Mitesh_Engr) February 7, 2020
To all. This is free learning for you. How to play option to make consistent return.
Stay tuned and learn it here free of cost. https://t.co/7J7LC86oW0
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