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Philip Vollet
@philipvollet 4 years, 1 month ago 525 views

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Why are graphs the future of biomedical research and what is the value of NLP here?

A small case study about:

How to speed up drug discovery with knowledge graphs and discover potential cures for diseases

In this case text mining is used to contextualize knowledge about:

- Genes
- Compounds
- Diseases
- Adverse drug effects
- Receptor bindings

Which text types are processed here? Medical literature, patient notes, electronic health records, clinical reports etc.

But how to start?

First you need to identify the different entities such as compounds, diseases, adverse drug effects and receptor bindings.

This is achieved through Natural Language Processing (NLP) and there are suitable pre-trained models for processing biomedical, scientific or clinical text like scispaCy

@spacy_io models for processing biomedical, scientific or clinical text
https://t.co/1EPFZCFwoc

Another library which is specialized in biomedical text is Spark NLP

@JohnSnowLabs

https://t.co/EYM8lIyuUp

The next challenge is to extract the different relations! Diseases are related to genes which are related to receptors and compounds can bind to these receptors.

Sounds simple at first but there are several problems that need to be solved

Problems to solve

1. Difficult to ingest and integrate complex networks of text mined outputs
2. Difficult to contextualize knowledge extracted from text with existing knowledge
3. Difficult to investigate insights in a scalable and efficient way

Fortunately, Grakn solves all our problems!

@GraknLabs

How it works is explained here: https://t.co/BCGDuWrVqA

To understand how NLP and graphs are used to link medical knowledge I recommend this talk on text mining and drug discovery at Novartis

Not quite up to date but aged very well

Connecting the Dots in Early Drug Discovery at Novartis
https://t.co/QNJt6q5IsU

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Lakshminarayan G
@narayanagl

The Chanting of following names of Bhagwan Vishnu, immensely helps us in overcoming the obstacles in our daily life.
These names are from Sri Vishnu Sahasranama!
|. "Om Vashatkaaraaya Namaha" : For Success in Business.
||. "Om Aksharaaya Namaha" : For Success in Studies.

|||. "Om Bhuthabhavanaya Namaha" : For Good Health.
|V. "Om Paramaathmane Namaha" : For Self Confidence.

Src: VAK magazine from Chilkur Balaji Temple, Hyderabad - Sri @csranga
#SanatanaDharma #SanatanaSanskriti #Sattology

One needs to chant the following slokas 28 times to get rid of certain problems in life.
Om Hrushikesaya Namah - For Overcoming Bad habits
Om Vashatkaaraya Namah - For Success in Business, Interviews, visa interviews, building relationships

Om Srimate Namah - For Handsome appearance & wealth
Om Aksharaya Namah - For Education & better financial strength
Om Paramatmane Namah - For self employed people, for promotions and success in games.
Om Putatmane Namah - To remove mental stress & for mental peace

Om Sarmane Namah - For Job Satisfaction
Om Bhutadaye Namah -To amend soured friendship or any personal relationship
Om Dhatre Namah - For issueless couple
Om vidhatre Namah - Pregnant Ladies to Chant for healthy babies.
Chant the following 108 times :

libertyandjusticeforal...
@Mark923to25

1. #Qanon told us that Saudi Arabia is a central piece of the puzzle in taking out the Deep State...we are watching the Deep State attempt to remove Crown Prince MBS and disrupt Pres Trump's administration's ties with MBS and the "new" Saudi/US coalition. Early in his admin,

2....@Potus sent Jared Kushner (JK) to SA on an undisclosed trip and told King Salman that business as usual was over, and if he wanted Pres Trump's support, Prince Alwaleed would have to be divested of $ and power; Alwaleed is one of top Deep State $ men and was tied to HRC.

3. @Potus knew that before he could begin cleansing the US and the rest of the world of the DS, he would have to cut one of the financial head's off the snake (Alwaleed). After JK met w/ King Salman, Alwaleed was arrested and divested of billions; MBS became leader of SA.

4. SA loves Pres Trump because he's a man of his word; SA could not trust Hussein or Clintons because they use SA for oil and leverage; SA has many factions, but essentially you have the new and upcoming SA that is attempting to modernize through Crown Prince MBS, and then you

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Khatvaanga
@khatvaanga

Starting my 2nd thread on Sringeri Parampara. This will cover the Jagadgurus after Sri Vidyaranya to Sri Shivabhinava Nrisimha Bharati.

It is really very tough to match the brilliance and achievements of Vidyaranya. After whom came 15 - Chandrashekara Bharati [1386-1389].

The next Acharya was Nrisimha Bharati [1389-1408]. Harihara raya found a town for this Acharya - Narasimhapuram. Acharya helped the king by guiding him in political affairs. He also initiated the kind with mahamantras for spiritual development.

Subsequent Acharyas were
15-Puroshottama Bharati [1408 - 1448]
16-Shankara Bharati[1448 - 1455]
17-Chandrasekhara Bharati II [1455 - 1464]
18- Nrisimha Bharati II [1464 - 1479]
19-Puroshottama Bharati II [1479 - 1517]

20-Ramachandra Bharati [1517 - 1560]. Sadashiva Raya was emporer of Vijayanagara during this time.
21-Nrisimha Bharati III [1560 - 1573]
22-Nrisimha Bharati IV [1573 - 1576]
23-Nrisimha Bharati V [1576 - 1600]

24-Abhinava Nrisimha Bharati [1600-1623]. When he visited Malahanikareswara temple for first time he noticed there was no Vinayaka there so he took piece of turmeric and drew outline of Ganesha on a pillar and offered puja.

Buzz Chronicles
@buzz_chronicles

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Angela Jamison
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$Anu Satheesh \U0001f1ee\U0001f1f3$

Anu Satheesh 🇮🇳...
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Yoga Ramar Temple
#Nedungunam
#TamilNaduTemples 🚩

Yoga Ramar Temple is located near Thiruvannamalai. Shri Rama is seated with eyes closed, without any weapons. Mata Sita pointing to the feet of Rama telling that everyone is safe at his feet. Lakshmana standing near Shri Rama

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Jai Sri Ram
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Anshul Pandey
@Anshulspiritual

IMPORTANCE OF SATYA NARAYAN KATHA AND ITS ORIGIN.

We all have heard and read the Satyanarayan katha. But none of us dont know the original stories that Shatanand or Sadhu or Kalavati must have heard. Also, as a habit we hear or read this katha

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The chorus of this song uses the shlokas taken from Sundarkand of Ramayana.

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1. धीवर प्रसार शौर्य भरा: The brave persevering one, your bravery is taking you forward.

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4. रौद्रमा नवा भीतिर्मा: His anger will cause new fears in his foes.

5.विजिटरीपुरु धीरधारा, कलोथरा शिखरा कठोरा: This is a complex expression seen only in Indic language poetry. The poet is stating that Shivudu is experiencing the intensity of climbing a tough peak, and likening

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Jaya_Upadhyaya
@Jayalko1

WEAPONS OF MAHADEV

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Here are some weapons associated with him:

TRISHULA: the 3 pointed blades denote creation, maintenance, and destruction or the 3 Kalas – Past, Present and Future. They also represent 3 Gunas – Sattva, Rajas and Tamas).
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@onlyonenetra @DetheEsha

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@iamkamyabuch @unever_followme

PARASHU: axe with 4 cutting edges which Shiva gave to Parashurama. In his anger, Parashurama used the parashu to get rid of the all the Earth’s tyrannical kshatriya caste twenty-one times over.
@harshasherni

CHANDRAHASA SWORD: The divine sword Chandrahasa literally means ‘the laughter of the moon’. Ravana gave this sword to Indrajit on different occasions especially to fight against Devas.
GIRISH: A special sword of Shiva with unique characteristics.