Wikipedia's current take on lab leak theory
https://t.co/lfTP7Rn3RY
Meanwhile the slugs are trying to erase all evidence of their censorship activities
https://t.co/VFhkbnT4kO
I do what I can but I am not Jesus, just a Monkey with a Mouse and WiFi

British Financed Hemiauchenia Slug Festival
search term "Wuhan"
https://t.co/2RZ770vDly
https://t.co/n1zGjuNxG7
https://t.co/ttZm1uWVSJ
Boing! said Zebedee! with a hatchet again!
"I'm collapsing this wall of text to reduce disruption caused by X, who is now blocked for 1 month from this article & its talk page under WP:GS/COVID19 sanctions.
The following discussion has been closed"
https://t.co/0wUBG8bNy3
More Censorship from the Gang of Slugs
-Thucydides411
"Agree with this, and nice tidy up job"
Britishfinance
https://t.co/0wUBG8bNy3
More Slug baiting and collaboration
@Britishfinance: I've followed your suggestion and added some material -Thucydides411
Thucydides411, nice work there and looks good. I think adding that the lab didn’t even have SARS-CoV-2 would also be worth it Thanks again. Britishfinance
More from Thucydides
Speaking of which, I find your musings above to be completely out of place on a Wikipedia talk page.
I find your attempts to personally discredit leading virologists to be really unacceptable. -Thucydides411
and here comes Boing! Said Fucking Zebedee to rescue Thucydides 411 when he is caught acting maliciously https://t.co/0wUBG8bNy3
Archived:
https://t.co/GJmX0jhuB6
"And Horse Eye's Back, please drop the confrontational attitude. Boing! said Zebedee"
Boing! Said Zebedee and Thucydides411 acting in a devious tandem slug attack
Earlier Observations https://t.co/i1YveYfGlc
https://t.co/uJHcsxla46
and a previous thread on wikipedia censorship and collusion
https://t.co/mSPCWCHNhP
Keep an eye on the French page
https://t.co/TyPkGPDf3E
Exposing the Wikipedia Slug Cartels
https://t.co/JE9B16qVqo via @TheSeeker268
WP user, LIXIAO9987. gets slugged to death over the inclusion of a Nature Article
https://t.co/8XwdULpEPX
by guess who?
Boing! said Zebedee and Thucydides411 again!
Archived: https://t.co/lQuOmAxGbM
Indian Wikipedia Slug Cartel tactics Investigation archived
https://t.co/Ps8Wr9JR15
More of their slug like antics here
https://t.co/XzWcS8AJRO
Archived: https://t.co/L8Ct0YNICF
and here:
https://t.co/DAh6UVC34u
Archived: https://t.co/PSjtrRaPO3

More from Billy Bostickson 🏴👁&👁 🆓

1/ Directed Evolution and Serial passage of RNA Viruses
A quick (I hope) thread on RNA viruses & some others, mainly for my own learning process, but also as evidence (as if it was needed) of what modern virology & microbiology is capable of doing to viruses in their laboratories

2/ In Vivo Continuous Directed Evolution
1 Recent advances in the field of in vivo continuous evolution
2 Advances in continuous culture of microbes enable continuous evolution
3 Viruses, prokaryotes, & eukaryotes mediate in vivo continuous evolution
https://t.co/BfR0B2Hwsf


3/ Continuous Directed Evolution of Biomolecules
By greatly accelerating laboratory evolution, PACE may provide solutions to otherwise intractable directed evolution problems and address novel questions about molecular evolution.
https://t.co/G3mIptI54H


4/ CDE for Strain & Protein Engineering
Inducible hypermutator systems accelerate strain evolution without compromising genome integrity.
Site-specific in vivo mutagenesis strategies have facilitated continuous protein engineering.
Automation

5/ Targeted mutagenesis:
A sniper-like diversity generator in microbial engineering
https://t.co/wdKyXghRYe
Advances in the directed evolution of proteins
https://t.co/1xXTtw1i3i
In vivo continuous directed evolution
https://t.co/xKRVSjVvo4
Same covid-19 mutations are appearing in different places, which may or may not be strange....
41,000 mutations documented in 880 lineages.
Most in spike protein
What explains it?


https://t.co/MvHzUb4peo


https://t.co/PAwgC3lgsO


https://t.co/f9rnyFI0vq


https://t.co/wAlyNzuI0W
1. I hate Tax Returns but these EcoDeath Alliance ones may be interesting to peruse:
2001: https://t.co/lws5YcYOwH
2002:
https://t.co/UOhCT2WrZR
2003:
https://t.co/GPaxtSHQWI
2005:
https://t.co/RPEK23bVzQ
2006:
https://t.co/6WYeJL2a8e
2007:

2. EcoDeath Alliance Tax Returns
2008:
https://t.co/27Pq9nx57i
2009:
https://t.co/KIcsoZP5tV
2010:
https://t.co/rJ1dq89hz9
2011:
https://t.co/txsItdtEwS
2012:

3. EcoDeath Alliance Tax Returns 2015 - 2020
2015:
https://t.co/BnMr9StUAR
2016 Audit:
https://t.co/jdBIPvAW3m
2016 Full Filing:
https://t.co/qBXdh4zeZ5
Form 990" for fiscal year ending June

4. Eco Death Alliance Tax Returns and Audits 2017
Audit for period ending June 2017
https://t.co/vjFt069KbY
Full Filing" for fiscal year ending June 2017
https://t.co/2a73SMm04U
Form 990" for fiscal year ending June

5. Eco Death Alliance Tax Returns and Audits 2018
Form 990 for period ending June 2018
https://t.co/WFdUnpe0dg
Audit for period ending June 2018
https://t.co/NwaKlSm8pV
"Full Filing" for fiscal year ending June
Compilation Thread on ORF8 ORF8 or Fate?
1. ZLS (2018):
"Considering the variability of orf8 in bats, civets and humans, investigating the function of orf8 is a priority, particularly the contribution of these different variants to viral pathogenesis."


2. ORF8 or Fate?
"In addition to receptor binding, proteolytic cleavage of S & potentially other mutations that affect virion & trimer stability may be important for virus transmissibility in different hosts, & these factors need to be studied

3. ORF8 or Fate?
Overwhelmingly these viruses had mutations or
29 deletions in ORF8 - associated with reduced replicative fitness of the virus.. may be associated with host adaptation
via @CarltheChippy
382-nt deletion during early evolution of

4. ORF8 or Fate?
@franciscodeasis reviewed the list of read filenames according to dates and labels:
- Sat 2017-06-03 (7896)
- Sat 2017-06-17 to Tue 2017-06-20 (7896 and ORF8)
- Thu 2018-09-27 to Sun 2018-09-30 (RaTG13)
- Mon 2018-10-08 to Sun 2018-10-14 (no label and TSS)


5. ORF8 or Fate?
What is ORF8? This is Orf8!
https://t.co/21ugtiinhL

More from All

#BhagavadGita Ch 2 Ver 23

नैनं छिन्दन्ति शस्त्राणि नैनं दहति पावकः |
न चैनं क्लेदयन्त्यापो न शोषयति मारुतः ||

Soul can never be cut into pieces by any weapon, nor can he be burned by fire, nor moistened by water, nor withered by the wind

#Suprabhatam 🙏
Jai Shree Krishna 🙏🌺


Bhagavad Gita, Chapter 6, Verses 26

यतो यतो निश्चरति मनश्चञ्चलमस्थिरम् |
ततस्ततो नियम्यैतदात्मन्येव वशं नयेत् ||

Whenever and wherever the restless and unsteady mind wanders, one should bring it back and continually focus it on God.

Suprabhatam🌺🙏
Jai Shree Krishna 🙏🌺


#BhagavadGita Chapter 2 Verse 48

योगस्थः कुरु कर्माणि संग त्यक्त्वा धनंजय ।
सिद्धयसिद्धयोः समो भूत्वा समत्वं योग उच्यते ॥

Perform your activities, giving up attachment and become equipoised in both success and failure. This is #Yoga.

Suprabhatam 🙏
Jai Shree Krishna 🙏🌺


#BhagavadGita Ch 2.63

क्रोधाद्भवति सम्मोह: सम्मोहात्स्मृतिविभ्रम: |
स्मृतिभ्रंशाद् बुद्धिनाशो बुद्धिनाशात्प्रणश्यति ||
Anger impairs judgment, which leads to loss of memory & thus the intelligence is destroyed; When the intellect is destroyed, one is ruined.

Suprabhatam 🙏🌺


#BhagavadGita Ch 3.5

न हि कश्चित्क्षणमपि जातु तिष्ठत्यकर्मकृत् |
कार्यते ह्यवश: कर्म सर्व: प्रकृतिजैर्गुणै:||

There is no one who can remain w.o action even for a moment. All beings, are compelled to act by three gunaas born of prakriti.

Suprabhatam 🙏
Jai Shree Krishna 🙏🌺

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A common misunderstanding about Agile and “Big Design Up Front”:

There’s nothing in the Agile Manifesto or Principles that states you should never have any idea what you’re trying to build.

You’re allowed to think about a desired outcome from the beginning.

It’s not Big Design Up Front if you do in-depth research to understand the user’s problem.

It’s not BDUF if you spend detailed time learning who needs this thing and why they need it.

It’s not BDUF if you help every team member know what success looks like.

Agile is about reducing risk.

It’s not Agile if you increase risk by starting your sprints with complete ignorance.

It’s not Agile if you don’t research.

Don’t make the mistake of shutting down critical understanding by labeling it Bg Design Up Front.

It would be a mistake to assume this research should only be done by designers and researchers.

Product management and developers also need to be out with the team, conducting the research.

Shared Understanding is the key objective


Big Design Up Front is a thing to avoid.

Defining all the functionality before coding is BDUF.

Drawing every screen and every pixel is BDUF.

Promising functionality (or delivery dates) to customers before development starts is BDUF.

These things shouldn’t happen in Agile.
1/ Some initial thoughts on personal moats:

Like company moats, your personal moat should be a competitive advantage that is not only durable—it should also compound over time.

Characteristics of a personal moat below:


2/ Like a company moat, you want to build career capital while you sleep.

As Andrew Chen noted:


3/ You don’t want to build a competitive advantage that is fleeting or that will get commoditized

Things that might get commoditized over time (some longer than


4/ Before the arrival of recorded music, what used to be scarce was the actual music itself — required an in-person artist.

After recorded music, the music itself became abundant and what became scarce was curation, distribution, and self space.

5/ Similarly, in careers, what used to be (more) scarce were things like ideas, money, and exclusive relationships.

In the internet economy, what has become scarce are things like specific knowledge, rare & valuable skills, and great reputations.