Age has nothing to do with delivery of good governance.. Yahaya Bello, Bukola Saraki, ORJI Uzor Kalu, Tunde Fashola, Rotimi Amaechi were all in their early/mid 40s when they became governors, we know what their report cards says as regards their performance...
There was a time

1/ The “I Have a Dream" speech is one of the most extraordinary speeches in American history. You should read it again. First, a few thoughts about the common American heritage Dr. King relied upon in calling Americans to rededicate themselves to the unfinished work of freedom.

2/ Dr. King delivered his speech in what he called the “hallowed spot” of the Lincoln memorial. More than a picturesque backdrop, King relied on America’s reverence for Lincoln and the common celebration of Lincoln’s words and acts, especially the Emancipation Proclamation.

3/ “Five score years ago…” King echoes the words of the Gettysburg Address. Like Lincoln, King invokes the Declaration of Independence and the fundamental principles of American freedom, “life, liberty and the pursuit of happiness.” Every person in that crowd knew these words.

4/ The Declaration, Constitution and Emancipation Proclamation declared and established the fundamental American principles of freedom that all Americans knew and believed in. But these principles and promises remained unfulfilled for black Americans.

5/ Lincoln’s audience knew the history of slavery and many had suffered personal loss in the ongoing war. Dr. King’s audience knew the history of violent racism, segregation, and unequal economic opportunity. The Proclamation freed the slaves, “but the Negro still is not free.”

I had the most bizarre experience outside of a bar yesterday, which my partner very aptly described as "toxic mask-unlinity." (A Thread.)

I was standing outside, waiting for a lyft to get home, when two cis men came out of the bar to smoke cigarettes. They're discussing the masks that folks are wearing in California at the moment because of the very dangerous air pollution from the fires happening.

I happen to be wearing one of those masks, because I think lungs are important and I like breathing. I dunno. One of the men notices me standing there, and says, "Like this f*cker right here. What is this shit?"

He goes on a homophobic rant about me, the pansy with a mask, and what a Very Manly Man he is because he's not afraid to smoke a pack of cigarettes while California is on fire. He doesn't need a mask, because something-something-heterosexual-something.

And part of me is just... impressed by the fact that this dude thinks he's Owning The Gay Libs by not wearing a mask to protect his lungs from smoke and particles in the air that are literally DANGEROUS... while chain-smoking. Outside of a bar.

Southerners wrote songs about Warrington, formed peace movements because of IRA violence - but I can’t point to any mainstream effort to oppose/understand who the glenane gang, or Shankill butchers were, care about Loughinisland, state violence, &collusion.
V selective interest

They were and are revolted by SF glorifying murder but dont know or care about the deaths of catholics here. As I’ve seen the apathy to the life my parents lived, and the fear I grew up with, I always make it understood I’m Irish but from the north. Because it’s important

Showing absolutely no interest in the murder of the people in the areas SF are elected to represent is really selectively deciding whose lives you think are worth anything. I doubt anyone south of Louth Monaghan or Cavan could tell you or care about the Reavey brothers

There was and is no hand wringing about children being shot in the fields by soldiers in front of their parents or hunted down in their own house and killed in front of their families- where were the marches, the songs, the movements?

“But Sinn Fein said this”- is of zero comfort to victims of state or loyalist violence and you are actually framing their loved ones murders in such a way that you’re almost making them partially culpable for their own fate or excusing it somehow when it’s nothing to do with SF

@avacta's AVA6000 approved by MHRA. Superb news. First dosing 'around mid-year'; first data to come within 3-4 months after that.

A summary thread on the significance of AVA6000 - and #AVCT's pre CISION platform as a whole - to both the oncology industry and to AVCT itself. 1/10

In very basic terms, #AVCT's pre CISION chemotherapies are essentially reformulated versions of existing, approved chemotherapies that have been used on cancer patients for many years - decades, even.

The pre CISION tech is simply an attempt to improve the safety profile... 2/10

...of the chemo.

Most therapeutics going through clinical trials look for an improvement of at least 20% over the existing industry-standard drug. A 50% increase in efficacy would usually be considered an astonishing result.

In pre-clinical mouse models for #AVCT's AVA6000 3/10

...18 times more pro-doxorubicin was found in the tumour than in the heart. Compare that to the 1:1 ratio of the standard doxorubicin.

What this means is that the pre CISION tech could be used to enable the giving of doses to patients that are multiple times more potent... 4/10

...than standard chemotherapy drugs - either in the form of greater number of cycles of chemo, or in the potency of the individual dose.

For example, in #AVCT's pre-clinical trials, pro-dox (AVA6000) doses were 6x more potent than the standard dox doses.

The results? The...5/10