HIKAL Annual Report is a must read for everyone tracking the CDMO/API/Intermediates industry.

HIKAL being a hybrid player, their Annual Report insights on Pharma, Animal Health and Crop

1/ Throughout my startup career, I’ve seen many founders have an aversion to sales. This is a mistake that can kill your startup.

2/ Sales is often viewed as either a saving grace or proof that the product isn’t good enough (because it should sell itself). Neither are ever true. Some common mistakes that result in...

3/ Mistake 1: Hire a sales rep before reaching product/market fit to get your initial batch of customers. This is a mistake because founders need to work through their MVP with early adopters to truly understand what it is they’re selling.

4/ Mistake 2: Reach product/market fit, need to scale, and rely entirely on self-serve. For enterprise products that require big commitments and internal shifts, almost no product is self-explanatory enough to sell itself.

5/ Mistake 3: Make a first sales hire who isn’t scrappy enough to help mold the sales process from scratch. Some salespeople are amazing at their jobs, but not cut out to establish the processes that others end up following. This skillset is what @rdedatta calls a “sales ninja”.

👇 Thread. New deck getting published this week: "Consumer startups are awesome, and here's what I'm looking to invest in at Andreessen Horowitz." If you want to read it, subscribe to my newsletter here: https://t.co/262t8eh0wf

1/ A lot of new consumer technologies have been introduced to US households in the last 100 years. But it's taken many of them - like the telephone - more than 50 years to get to the majority of the US. Why is that?

2/ We had to literally teach people how to use phone. Which end goes to your mouth, which goes to your ear. Say "hello" when people call. The motivation of consumers to talk to their friends has always been there, but we had to teach the behavior

3/ If you compare phones to the latest technologies, there's been a huge shift. Things are being picked up much faster.

4/ Even while there's been all this innovation recently, physically speaking, we are still the same human beings from 100,000 years ago.

THREAD: What is Golden Crescent and Golden Triangle and how it impacts India?

Golden Crescent region of South Asia - comprises of Afghanistan, Iran, and Pakistan - which is a principal global site for opium production and distribution.

Golden Triangle is the area where the borders of Thailand, Laos and Myanmar meet at the confluence of the Ruak and Mekong rivers. The Golden Triangle is called so because of the triangular shape formed by the locations of New Delhi, Agra and Rajasthan on a map.

India is wedged bw world’s 2 largest areas of illicit opium production, Golden Crescent & Golden Triangle, that has made Indian borders vulnerable to drug trafficking. It flows from 2 fronts, NW & NE, that possesses dual concern - violation of border & threat to national security

- Golden Crescent is world’s leading opium and cannabis producing region since 1983.

- Its proximity to Indo-Pak border has worsened the trafficking of hashish and heroin into Indian soil

- Trafficking happens through the border states of J&K, Punjab, Rajasthan and Gujarat.

- Golden Triangle is leading opium producing region of the South-east Asia, also an ancient narcotics supply route to North America & Europe.

- Myanmar-Northeast nexus is recognized by NCB as the root of heroin & chemical drugs

- Myanmar produces 80% of heroin produced in world

An interesting set of games that I've been vaguely interested in since I was a kid, after seeing one at a friend's house and never being able to find it again, was the BATTLES IN A DISTANT DESERT/BATTLES ON DISTANT PLANETS series.

These are turn-based wargames for windows 3.x, sharing the same engine.
Battles in a Distant Desert is from 1992, and is based on the first Iraq war (Desert Storm)

and Battles on Distant Planets is from 1991, and takes place in SPACE!
I'm pretty sure this is the one I played as a kid.

They've got 3 options to play with:
* Player vs. Player
* Player vs. Computer
* Computer vs. Computer

So it's a 0-2 player game!

They also did a DOS strategy game called "STARDATE 2140.2: GALACTIC CONQUEST" in 1990, but it seems to be lost.
All the games share an experimental AI system based on neural networks.

1/OK, I should really write another thread about university-centric regional development, because I think people often make some (very understandable) mistakes when thinking about this issue.

2/The biggest myth, I think, is that universities help regions by educating locals as undergraduates.

Skeptics of universities say: "But most of the people who graduate end up leaving."

3/In fact, most of what a university does for a regional economy is NOT about educating local kids.

Educating local kids is good for the nation, but doesn't help a region much.

The way a university helps a region is through

4/Undergraduates usually leave town after graduation.

But university RESEARCH pulls in OTHER smart people from other regions, and they stay there.

Here's a paper showing that this is the main way universities increase a region's human capital:

5/Research also pulls in business investment.

Companies want to partner with university labs, so they can commercialize the technologies the labs produce. So they invest in the labs, and sometimes they even put their offices in the town.