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The new Variant Under Investigation (VUI) was re-designated Variant of Concern (VOC) 202012/01 on 18 December
This is an excellent report by @PHE_UK, but it’s a bit technical so I’ll try to unpick it for you
https://t.co/M9f3zaimF5
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90% were from <60 years old (further detail not yet available here)
6 patients had already died
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Of note, 3 of the main testing labs use a PCR test for 3 different viral genes: N, ORF1ab, S.
The new VOC has a mutation that makes this test negative for S (spike), but positive for the others.
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Because of the way genetics works, 6 of these don’t actually change viral proteins (so-called synonymous mutations).
13 change amino acids of a viral protein (see Figure)
4 remove a small piece of a protein
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https://t.co/f5JWWUOaqy
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Although N501Y has not yet been tested, other mutations at 501 decrease the effectiveness of LYCoV016, a monoclonal antibody developed to treat COVID19
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They deserve our thanks!
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https://t.co/hT5XPkTepy #english #wiki #wikidiff
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Another common #question:
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2. The heritability of IQ *increases* from childhood to adulthood. Meanwhile, the effect of the shared environment largely fades away. In other words, when it comes to IQ, nature becomes more important as we get older, nurture less. https://t.co/UqtS1lpw3n
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1. IQ is one of the most heritable psychological traits – that is, individual differences in IQ are strongly associated with individual differences in genes (at least in fairly typical modern environments). https://t.co/3XxzW9bxLE
2. The heritability of IQ *increases* from childhood to adulthood. Meanwhile, the effect of the shared environment largely fades away. In other words, when it comes to IQ, nature becomes more important as we get older, nurture less. https://t.co/UqtS1lpw3n
3. IQ scores have been increasing for the last century or so, a phenomenon known as the Flynn effect. https://t.co/sCZvCst3hw (N ≈ 4 million)
(Note that the Flynn effect shows that IQ isn't 100% genetic; it doesn't show that it's 100% environmental.)
4. IQ predicts many important real world outcomes.
For example, though far from perfect, IQ is the single-best predictor of job performance we have – much better than Emotional Intelligence, the Big Five, Grit, etc. https://t.co/rKUgKDAAVx https://t.co/DWbVI8QSU3
5. Higher IQ is associated with a lower risk of death from most causes, including cardiovascular disease, respiratory disease, most forms of cancer, homicide, suicide, and accident. https://t.co/PJjGNyeQRA (N = 728,160)