The behaviours of the virus do not depend on the current ‘zone’ of public health restrictions. And, to be perfectly candid, neither should ours. (2/14)
THIS IS A CATCHY & ATTENTION-GRABBING TITLE
Today, the Province will likely announce what zone of the reopening framework we'll shift into as of Tuesday. Whatever is announced, though, doesn't change what we need to do. Why?
Kindly read these 14 tweets & we'll tell you. (1/14)
The behaviours of the virus do not depend on the current ‘zone’ of public health restrictions. And, to be perfectly candid, neither should ours. (2/14)
Nurses, doctors, paramedics & healthcare workers have experienced things much differently than most of us. (3/14)
Business owners & hospitality workers have been on a rollercoaster of openings & closures.
Students, parents, teachers & school staff have had to adapt to going from online (4/14)
And this virus has disproportionately affected some groups more than others.
But there's the thing: while our experiences of this pandemic haven't been shared, we do have a shared goal.
And we can reach it together. (5/14)
Want to help ensure that once our local businesses reopen, they stay open? We can wear masks & physically distance. (6/14)
Helping those who are isolated or have been disproportionately affected? We must get our vaccines when our time comes. (7/14)
Between now and then, we'll be following our COVID-19 Vaccination Plan: https://t.co/WoFmxjyXHW. (8/14)
No one is perfect. In fact, other than the song Tiny Dancer, perfection doesn't exist.
Yes, some of us haven't been 100% #COVIDwise every day. (9/14)
Our actions matter. We know the lack of instant gratification is hard. (10/14)
It's about knowing our actions now will pay dividends later.
And with the new variants, we don't have a choice but to be as vigilant as we can, every day. (11/14)
If you ♥️ or RT this, do it because you're committing. Make it a sign. Your way of saying to your followers that you're on board.
And you won't be alone. (12/14)
More from Health
1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?
And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?
For answers, we'll have to go back a few billion years.
2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.
Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine
But why does DNA contains thymine (T) instead of uracil (U)?
https://t.co/XlxT6cLLXg
3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).
In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?
https://t.co/bIZGviHBUc
4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.
DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.
https://t.co/bIZGviHBUc
5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.
When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.
[*Note: thymine is the base in dTMP]
https://t.co/AnDUtKkbZh
Why do B12 and folate deficiencies lead to HUGE red blood cells?
And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?
For answers, we'll have to go back a few billion years.
2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.
Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine
But why does DNA contains thymine (T) instead of uracil (U)?
https://t.co/XlxT6cLLXg
3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).
In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?
https://t.co/bIZGviHBUc
4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.
DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.
https://t.co/bIZGviHBUc
5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.
When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.
[*Note: thymine is the base in dTMP]
https://t.co/AnDUtKkbZh
