Pharma learnings 101:

Higher the difficulty to manufacture, Lower the competition, Higher the pricing power.

Higher the regulatory oversight, the Bigger is the moat for those who comply.

#PharmawithJST

Did you know?

Rani Bhabani was the Queen of Natore, Bengal or 'Natorer Rani' as she was famously called. She made great contributions in Tarapith & renovated Benaras.

In Varanasi, Durga Kund Mandir was constructed by Rani Bhabani in the 18th century.

Born in Chhatimgram village, Bogra District,Her father's name was Atmaram Choudhury.Bhabani was married off to Raja Ramkanta Moitra,the then zamindar of Rajshahi.After his death, Bhabani became the zamindar, and started being referred to as Rani.She was known as Ardhabangeshwari.

A woman as a zamindar was extremely rare in those days, but Rani Bhabani managed the vast Rajshahi zamindari most efficiently and effectively for over four decades.
Maharani Bhavani was very pious in her personal life. She passed her life in a strict disciplined way.

She conducted the administrative work skillfully. As a Maharani she was an impartial judge. Rani Bhavani had a very hard time during the fag end of her life. The Zamindari (estate) incurred serious loss due to the change of the revenue policy of the company.

In spite of being the owner of a large Zamindari (estate), she had to depend on the stipend of the government in the later part of her life. The amount of this stipend gradually decreased and became Rs. 1000/- only in the end.

शमशान में जब महर्षि दधीचि के मांसपिंड का दाह संस्कार हो रहा था तो उनकी पत्नी अपने पति का वियोग सहन नहीं कर पायी और पास में ही स्थित विशाल पीपल वृक्ष के कोटर में अपने तीन वर्ष के बालक को रख के स्वयं चिता पे बैठ कर सती हो गयी ।इस प्रकार ऋषी दधीचि और उनकी पत्नी की मुक्ति हो गयी।

परन्तु पीपल के कोटर में रखा बालक भूख प्यास से तड़पने लगा। जब कुछ नहीं मिला तो वो कोटर में पड़े पीपल के गोदों (फल) को खाकर बड़ा होने लगा। कालान्तर में पीपल के फलों और पत्तों को खाकर बालक का जीवन किसी प्रकार सुरक्षित रहा।

एक दिन देवर्षि नारद वहां से गुजर रहे थे ।नारद ने पीपल के कोटर में बालक को देख कर उसका परिचय मांगा -
नारद बोले - बालक तुम कौन हो?
बालक - यही तो मैं भी जानना चहता हूँ ।
नारद - तुम्हारे जनक कौन हैं?
बालक - यही तो मैं भी जानना चाहता हूँ ।

तब नारद ने आँखें बन्द कर ध्यान लगाया ।

तत्पश्चात आश्चर्यचकित हो कर बालक को बताया कि 'हे बालक! तुम महान दानी महर्षि दधीचि के पुत्र हो । तुम्हारे पिता की अस्थियों का वज्रास्त्र बनाकर ही देवताओं ने असुरों पर विजय पायी थी।तुम्हारे पिता की मृत्यु मात्र 31 वर्ष की वय में ही हो गयी थी'।

बालक - मेरे पिता की अकाल मृत्यु का क्या कारण था?
नारद - तुम्हारे पिता पर शनिदेव की महादशा थी।
बालक - मेरे उपर आयी विपत्ति का कारण क्या था?
नारद - शनिदेव की महादशा।
इतना बताकर देवर्षि नारद ने पीपल के पत्तों और गोदों को खाकर बड़े हुए उस बालक का नाम पिप्पलाद रखा और उसे दीक्षित किया।

Хајде да направимо мали осврт на случај Мика Алексић .

Алексић је жртва енглеске освете преко Оливере Иванчић .
Мика је одбио да снима филм о блаћењу Срба и мењању историје Срба , иза целокупног пројекта стоји дипломатски кор Британаца у Београду и Оливера Иванчић

Оливера Илинчић је иначе мајка једне од његових ученица .
Која је претила да ће се осветити .

Мика се налази у притвору због наводних оптужби глумице Милене Радуловић да ју је наводно силовао човек од 70 година , са три бајпаса и извађеном простатом пре пет година

Иста персона је и обезбедила финансије за филм преко Беча а филм је требао да се бави животом Десанке Максимовић .
А сетите се и ко је иницирао да се Десанка Максимовић избаци из уџбеника и школства у Србији .

И тако уместо романсиране верзије Десанке Максимовић утицај Британаца

У Србији стави на пиједестал и да се Британци у Србији позитивно афирмишу како би се на тај начин усмерила будућност али и мењао ток историје .
Зато Мика са гнушањем и поносно одбија да снима такав филм тада и почиње хајка и претње која потиче из британских дипломатских кругова

Најгоре од свега што је то Мика Алексић изговорио у присуству високих дипломатских представника , а одговор је био да се све неће на томе завршити и да ће га то скупо коштати .
Нашта им је Мика рекао да је он свој живот проживео и да могу да му раде шта хоће и силно их извређао

In 1937, a trucker got frustrated waiting for his cargo to be unloaded. He later sold his company for $1.1 billion.

Here’s the story of how Malcom McLean made a billion dollars and which startup could be following in his footsteps. (Inspired by our episode with @laurabehrenswu)

In the early 1950s, the shipping industry was a dying business.

New York’s docks were handling half as much domestic cargo in the early 1950s as they had been in the depressed 1930s.

In thirty years, no one had invested significant money in coastal shipping.

Why?

As McLean found out, loading ships was difficult and slow.

A truck or train would deliver items to the port. Each item was unloaded separately, recorded, and carried to storage.

When a ship was ready, each item was taken from storage, counted again, and hauled on-board.

The cost of this labor was significant. As one expert at the time explained:

“A four-thousand-mile voyage for a shipment might consume 50 percent of its costs in covering just the two ten-mile movements through two ports.”

Yet, despite the industry’s issues, it felt little pressure to change.

Foreigners were barred from operating domestically. Cartels ran international routes. And gov. subsidies eased the pain of labor costs.

Reshaping the industry needed an outsider.

Enter Malcolm McLean.

Ever notice how the top niches are centered around health, wealth, and relationships?

There's a deep-rooted psychological (and biological) reason why.

And today, I'm gonna to explain all of it so you can start profiting off of this knowledge 💰💰

*Now, this thread is going to be long and in depth. Make sure to favorite the top tweet now so you can come back to it later.

So. Down to the very core of every living being (humans, dolphins, bacteria, aliens), there are only two drivers:
1. To survive
2. To reproduce

Right off the bat, we know that sex is a primary driver to human behavior.

This would also mean that each gender has its own insecurities regarding sex.

Men have a subconscious fear that their woman will leave them for someone more successful

Women have a fear that their man will leave them for someone younger & better-looking

We can conclude that men are attracted to looks, and women are attracted to status.

This is human nature down to its very core.

Crazy, blue-haired feminists will try to argue and say otherwise.

But, 50 years of feminism DOES NOT OVERRIDE millions of years of evolutionary biology.

Here's a quick visualization exercise so you can see how true all this is...