It has been instructive to look back at our tweets re' the pandemic from early in 2020. So here are the questions we have today as we start in 2021. Feel free to add to the list. Let us see how these age a year from now:
1/n👇

1. Getting the world vaccinated -
How can we get the vaccine to everyone? First, we must make enough, then overcome the hesitancy, solve the problems of logistics of distribution and administration. We are struggling in all these areas.
2/n 👇
2. The dosing regimen-
Is it better to give 1 dose of 2-dose regimen to more people vs. give both doses to few?
Data from both Pfizer and Moderna vaccines that if you look at the cases after 12 days of 1st shot to the second shot, the efficacy may be in 80-90% range
3/n 👇
3. Vaccine prioritization:
Should we first give the vx to younger HCWs to keep hospitals open or to all the elderly who are likely to be sicker and the reasons hospitals will be overwhelmed?
Israel is doing a fantastic job getting all the elderly vaccinated first.
4/n 👇
4. Variant strains:
RNA virus tend to mutate. Vx are targeting the Spike protein of the Sars-Cov-2. Will there be enough mutation at critical points to make the virus resistant to the Vx?
This will require regular sequencing/monitoring. Besides the UK, who will do this?
5/n 👇
5. Duration/typeof immunity:
How long will immunity from Vx and natural infection last? Immunity is >just antibodies. Complex to study. (see #2 above - what if we give only 1 dose?).
Also, will Vx prevent transmission?
6/n 👇
6. Development of Public Health/Pandemic preparedness
Will we put in place permanent public health and pandemic preparedness plans with long-term funding that cannot be taken away by the whim of a political party?
7/n 👇
7. Science
Separate Science from politics - figure out an ideal system that provides balanced transparent independent scientific input to make public health decisions.
8/n 👇
8. Misinformation
Work with various stakeholders to help control and tap down on misinformation particularly via social media. This is unlikely to be solved in 2021.
9/n 👇
9. Health & economy
Reflect on 2020 and be honest in recognizing that health and economy are inextricably linked. You cannot have one without the other. Study the models adopted by various countries, find best practices & socialize these to be ready for next pandemic.
10/n 👇
10. Disparities
Outcomes driven by socio-economic disparities, structural racism in systems controlled by the rich and privileged laid bare how uncaring and self-centered humans can be. Will any country change its approach to ensure each citizen has equal right to be healthy?

More from For later read

There is some valuable analysis in this report, but on the defense front this report is deeply flawed. There are other sections of value in report but, candidly, I don't think it helps us think through critical question of Taiwan defense issues in clear & well-grounded way. 1/


Normally as it might seem churlish to be so critical, but @cfr is so high-profile & the co-authors so distinguished I think it’s key to be clear. If not, people - including in Beijing - could get the wrong idea & this report could do real harm if influential on defense issues. 2/

BLUF: The defense discussion in this report does not engage at the depth needed to add to this critical debate. Accordingly conclusions in report are ill-founded - & in key parts harmful/misleading, esp that US shldnt be prepared defend Taiwan directly (alongside own efforts). 3/

The root of the problem is that report doesn't engage w the real debate on TWN defense issues or, frankly, the facts as knowable in public. Perhaps the most direct proof of this: The citations. There is nothing in the citations to @DeptofDefense China Military Power Report...4/

Nor to vast majority of leading informed sources on this like Ochmanek, the @RANDCorporation Scorecard, @CNAS, etc. This is esp salient b/c co-authors by their own admission have v little insight into contemporary military issues. & both last served in govt in Bush 43. 5/
the whole point of Dunks was you could go cop them at VIM whenever you wanted for $65. this shit is like having to enter a raffle to buy milk.


like seriously why not make a ton more of them if they're gonna be so sought-after? they land at outlets? so? nike still makes money off that.

the only reason to keep making them so limited is that they KNOW all that matters is the profit on the flip and if they were readily available FEWER people would want them, not more

the whole system is super broken, but it's just gonna go the way it goes, because at this point it all caters to the secondary market. the only reason Nike can sell Jordan 1s for $200 is because the people buying them can flip them for $500

adjusted for inflation, a $65 AJ1 in 1985 is like $160—and modern-day AJ1s are made from cheaper materials in factories staffed by cheaper workers. they don't HAVE to be $200 retail. but the secondary market nuked the whole concept of what sneakers are "worth"

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