Mini Hungarian language lesson: house of cards
A historic house being demolished to make way for yet another hotel is an everyday occurrence in downtown Budapest.
But today's news about the demise of the house that used to host the pub called "The Wichmann" is sadder than most.
Then in 2018 it was announced the pub will be sold; Wichmann was 70 at the time and said he was just tired and old. He died less than two years later
Take a look at this gate ornament for example. If your first reaction is WTF?, I'm not blaming you.
For this house used to be the home of the Theosophical Society of Hungary in the first half of the 20th century.
It reportedly stood out from the neighbouring upmarket brothels by dint of the women working there taking a bath not once but twice a week.
But not all innovations in this house were of a pubic nature.
Of course no-one else outside of Hungary calls it that, it's called Swiss/Tell or Seasons Pattern, or Doppeldeutsche in German.
As you can also see, this is a picquet pack with only 32 cards.
In 1836 censorship was pretty strict, so Hungarian heroes would've been right out. But the story of William Tell is still a nod to the struggle and liberation from the Habsburgs.
And instead of Jacks and Queens we have Alsó ("lower") and Felső ("upper"), or archaically "filkó".
I don't know if Stüssi was particularly dim in the original story but there we are.
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Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs