PFIZER VACCINE
— Paradigm Shift Platforms (@Shift_Platforms) January 26, 2021
Rate...
Relative measure of effect (incidence rate ratio):
(8 cases/2,214 person-years) / (162 cases/2,222 person-years)
= 0.05
or a 95% less rate of occurrence of #COVID19 cases for vaccine vs. placebo pic.twitter.com/Qg1Em914Cv
THREAD
Breaking down the “efficacy” and safety of the #COVID19 vaccines if applied to the population
MODERNA VACCINE
— Paradigm Shift Platforms (@Shift_Platforms) January 26, 2021
Only RISK- (& not rate-) related measures are provided for Moderna...
Relative measure of effect (incidence risk ratio):
(11 cases/14,134 persons) / (185 cases/14,073 persons)
= 0.06
or a 94% less risk of occurrence of #COVID19 cases for vaccine vs. placebo pic.twitter.com/xiZPi6QXH8
ASTRAZENECA VACCINE
— Paradigm Shift Platforms (@Shift_Platforms) January 26, 2021
Rate...
Relative measure of effect (incidence rate ratio):
(44.1 cases/1,000 person-years) / (149.2 cases/1,000 person-years)
= 0.296
or a 70.4% less rate of occurrence of #COVID19 cases for vaccine vs. placebo pic.twitter.com/OJD6xeOksq
^ Are those 0.13% less #COVID19 cases worth the development of an expected 20.7% or 1,614,000,000 related adverse events (of which 1,443,042 would be serious) over a week (and completely unknown magnitude of related adverse events beyond this first week)?https://t.co/w6VSAuFZcg pic.twitter.com/Cl1hVx5XT0
— Paradigm Shift Platforms (@Shift_Platforms) January 26, 2021
^ Are 1.2% less cases in 2 months worth development of 8.2% or 637,971,682 related adverse events (of which 71,913,072 would require medical attention and 3,081,988 be serious) over 28 days (and unknown magnitude of related adverse events beyond 28 days)?https://t.co/j0uD21d9iK pic.twitter.com/sE0KLjkSR0
— Paradigm Shift Platforms (@Shift_Platforms) January 26, 2021
^ Are those 1.2% less #COVID19 cases worth the development of an expected 0.7% or 62,400,000 adverse events (of which 54,600,000 would be serious) over ~6 weeks (and completely unknown magnitude of adverse events beyond these first ~6 weeks)?https://t.co/nUliSrTkWi pic.twitter.com/okFMzqBL5d
— Paradigm Shift Platforms (@Shift_Platforms) January 26, 2021
Given that only ~1 in 5 #COVID19 cases require hospitalization, this means that only ~20% of the already minute levels of decreases provided by vaccines in the occurrence of #COVID19 would prevent #COVID19 leading to hospitalizations...
https://t.co/UD5pIQjIY2
* Pfizer vaccine would lead to only ~0.03% less #COVID19 hospitalizations over 1 week
* Moderna vaccine would lead to only ~0.24% less #COVID19 hospitalizations over 2 months
* AstraZeneca vaccine would lead to only ~0.24% less #COVID19 hospitalizations over 6 weeks
* Pfizer vaccine would cause 1,443,042 serious adverse events over 1 week
* Moderna vaccine would cause 3,081,988 serious adverse events over 28 days
* AstraZeneca vaccine would lead to 54,600,009 serious adverse events over 6 weeks
https://t.co/9Ckp1Fy53h
Further, niacin is a safe, natural vitamin; readily available; & would cost <1 cent a gram in bulk https://t.co/rAFMIHzUeA
Sufficient niacin supply: the missing puzzle piece to COVID-19, and beyond?https://t.co/gHcfOcekcf
— Paradigm Shift Platforms (@Shift_Platforms) January 20, 2021
Sensational results are being observed per below PROTOCOL
If NIACIN has helped you/loved one for #COVID19 (or anything else), please elaborate on the experience in comments below https://t.co/BthaRndiWV pic.twitter.com/yFsP6A3VDs
Beyond brief follow-up, they could very well even exasperate burden of disease outcome (i.e. #COVID19 hospitalizations) that they intend to & do initially—albeit meaninglessly—protect against!
https://t.co/ROir4ebMjB
85% efficacy does not mean 85% less cases. Stop misleading the public with your influence by whether carelessly or intentionally avoiding dissemination of actually interpretable communications of public health impact.
— Paradigm Shift Platforms (@Shift_Platforms) January 30, 2021
See through here https://t.co/QyXBgDn4zx
More from All
https://t.co/6cRR2B3jBE
Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.
https://t.co/FBfXhUrH5d
Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.
...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.
Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.
Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.
https://t.co/FBfXhUrH5d
Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.
...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.
Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.
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Department List of UCAS-China PROFESSORs for ANSO, CSC and UCAS (fully or partial) Scholarship Acceptance
1) UCAS School of physical sciences Professor
https://t.co/9X8OheIvRw
2) UCAS School of mathematical sciences Professor
3) UCAS School of nuclear sciences and technology
https://t.co/nQH8JnewcJ
4) UCAS School of astronomy and space sciences
https://t.co/7Ikc6CuKHZ
5) UCAS School of engineering
6) Geotechnical Engineering Teaching and Research Office
https://t.co/jBCJW7UKlQ
7) Multi-scale Mechanics Teaching and Research Section
https://t.co/eqfQnX1LEQ
😎 Microgravity Science Teaching and Research
9) High temperature gas dynamics teaching and research section
https://t.co/tVIdKgTPl3
10) Department of Biomechanics and Medical Engineering
https://t.co/ubW4xhZY2R
11) Ocean Engineering Teaching and Research
12) Department of Dynamics and Advanced Manufacturing
https://t.co/42BKXEugGv
13) Refrigeration and Cryogenic Engineering Teaching and Research Office
https://t.co/pZdUXFTvw3
14) Power Machinery and Engineering Teaching and Research
1) UCAS School of physical sciences Professor
https://t.co/9X8OheIvRw
2) UCAS School of mathematical sciences Professor
3) UCAS School of nuclear sciences and technology
https://t.co/nQH8JnewcJ
4) UCAS School of astronomy and space sciences
https://t.co/7Ikc6CuKHZ
5) UCAS School of engineering
6) Geotechnical Engineering Teaching and Research Office
https://t.co/jBCJW7UKlQ
7) Multi-scale Mechanics Teaching and Research Section
https://t.co/eqfQnX1LEQ
😎 Microgravity Science Teaching and Research
9) High temperature gas dynamics teaching and research section
https://t.co/tVIdKgTPl3
10) Department of Biomechanics and Medical Engineering
https://t.co/ubW4xhZY2R
11) Ocean Engineering Teaching and Research
12) Department of Dynamics and Advanced Manufacturing
https://t.co/42BKXEugGv
13) Refrigeration and Cryogenic Engineering Teaching and Research Office
https://t.co/pZdUXFTvw3
14) Power Machinery and Engineering Teaching and Research
1/ Here’s a list of conversational frameworks I’ve picked up that have been helpful.
Please add your own.
2/ The Magic Question: "What would need to be true for you
3/ On evaluating where someone’s head is at regarding a topic they are being wishy-washy about or delaying.
“Gun to the head—what would you decide now?”
“Fast forward 6 months after your sabbatical--how would you decide: what criteria is most important to you?”
4/ Other Q’s re: decisions:
“Putting aside a list of pros/cons, what’s the *one* reason you’re doing this?” “Why is that the most important reason?”
“What’s end-game here?”
“What does success look like in a world where you pick that path?”
5/ When listening, after empathizing, and wanting to help them make their own decisions without imposing your world view:
“What would the best version of yourself do”?
Please add your own.
2/ The Magic Question: "What would need to be true for you
1/\u201cWhat would need to be true for you to\u2026.X\u201d
— Erik Torenberg (@eriktorenberg) December 4, 2018
Why is this the most powerful question you can ask when attempting to reach an agreement with another human being or organization?
A thread, co-written by @deanmbrody: https://t.co/Yo6jHbSit9
3/ On evaluating where someone’s head is at regarding a topic they are being wishy-washy about or delaying.
“Gun to the head—what would you decide now?”
“Fast forward 6 months after your sabbatical--how would you decide: what criteria is most important to you?”
4/ Other Q’s re: decisions:
“Putting aside a list of pros/cons, what’s the *one* reason you’re doing this?” “Why is that the most important reason?”
“What’s end-game here?”
“What does success look like in a world where you pick that path?”
5/ When listening, after empathizing, and wanting to help them make their own decisions without imposing your world view:
“What would the best version of yourself do”?
