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1/ This month we'll learn whether the US is a banana republic ruled by election fraud or a constitutional republic based on attempted election integrity.

#GodSaveTheRepublic #AdjudicateFraud #FraudMatters #EvidenceMatters #MassiveFraudEvidence


2/ Judges refuse to review fraud evidence based on an alleged lack of standing. Why do illegal aliens have more standing in the US? Louie Gohmert on Pence: 'ignore all electors' and choose a winner as he sees fit' https://t.co/OHbSpEEPnp

#Trump2021 #Amendment12 #ElectoralVote


3/ Are Mike Pence and the 12th Amendment January 6th the last hope to save the US Republic from becoming the perpetually corrupt US Banana Republic tossed into the waste bin of history?

https://t.co/7HYkLVfAq3

#ElectionFraud #BananaRepublic #Amendment12 #January6 #Jan6th


4/ Election fraud increases daily: EXCLUSIVE: Fraudulent Georgia Ballots Were Addressed to Elections Consultant Dwight Brower - The Same Guy Who Reported the Fake Water Main Break and Then Terminated Election Whistleblower via @gatewaypundit https://t.co/RkgSD0wwXf #StopTheSteal

5/ Donald Trump's correct. The Georgia Senate runoffs are illegal and invalid, STILL using illegal Dominion, owned and influenced by hostile foreign election interference, against 2018 EO prohibiting Foreign Election Interference.
https://t.co/J1pJ9fPrqh via @whitehouse
Here's a thread of all of @LLinWood's recent 🔥 tweets for your safe keeping.
This issue is, appropriately, contentious. As a vaccinologist - & citizen & relative of people in at-risk groups - I fully support the UK decision to increase dose intervals of both our Ox/AZ product and the Pfizer product. I'd happily receive either with a >8w gap. Here's why 🧵


For the Ox/AZ vaccine, it's fairly simple. The trial demonstrated efficacy at a range of dose intervals. Antibody responses after the boost were significantly stronger with longer intervals - see table

(so in response to @drmarkporter's point, higher immune responses with a longer interval is proven & now public. I haven't seen a similar analysis for efficacy against disease but the data exists and I suspect the regulators & JCVI committee have)

For Pfizer, there isn't direct evidence of efficacy with a >3wk interval. But as widely publicised, efficacy in the period from 14 days after first dose to 21 days is high.


Can we extrapolate from this to a longer interval? It's a judgment call. On one hand is evidence-based medicine's scepticism of anything not directly proven 'beyond reasonable doubt' in an RCT; on the other is a 'balance of probabilities' approach based upon the biology.
THREAD
There’s much debate around the UK's recommended use of the AZ vaccine with a two-dose schedule and flexible timing of second dose. Some thoughts on the AZ recommendation (not Pfizer) based on available data with refs to some excellent threads.


UK’s MHRA and JCVI are highly-experienced in vaccine assessments and recommendations, and they've surely weighed the benefits & risks of this recommendation carefully. That said, it would be good to see all the data underpinning their recommendation.


In general, vaccines should be taken on a schedule tested in an efficacy trial. But it wasn’t possible to conduct the typical dose and schedule optimization prior to these Ph3 trials, and those trials provided valuable data to inform these recommendations. 3/

The UK recommends a two-dose schedule, with the second dose between 4-12 weeks. This *is not* a single dose schedule. Given the data provided, and in the setting of limited supply, overstretched hospitals, and emergence of a more transmissible variant, this seems justifiable. 4/

The UK has important data on the AZ Vx that wasn’t available for Pfizer & Moderna at FDA's VRBPAC, including:
* single-dose efficacy through 4+ months; and
* single-dose immunogenicity (12+ weeks).
Yesterday I spent time (&far too many tweets) trying to defend @Keir_Starmer 's position in a Guardian article which angered & disappointed many who, like me, are passionate pro-Europeans. I will try to explain why (thread)


Starmer is like me a lawyer, not a trade specialist but he obviously took advice. He is also a committed pro-European. As a lawyer when looking at the TCA, I saw all the predicted negatives but also enormous potential for a pro-EU government which results from the

institutional structure of the deal. The TCA sets up 19 specialised committees (including on Customs Cooperation, SPS, Technical Barriers to Trade) dominated by an all powerful 50/50 Partnership Council (PC) which takes binding decisions with immediate direct effect by agreement.

These decisions do not have to be published or not in full. This is undemocratic but typical of FTAs and efficient. In my view there is huge potential to take big decisions, far from the emotional tone of the Brexit drama, decisions which will be crouched in technocratic language

"Removing the red tape" " Customs Simplifications Procedure" (a lesser form of CU), "mobility", "improving access for services (a lesser form of FoM): little by little, step by step, the most negative effects of the TCA will be undone out of the glare of the tabloid press until
Today's threads (a thread).

Inside: My Fellow Americans; Digital manorialism vs neofeudalism; SC GOP moots modest improvements to "magistrate judges"; Pavilions replacing union workers with "gig workers"; and more!

Archived at: https://t.co/X4sEk5g09z

#Pluralistic

1/


My Fellow Americans: Audio, text and commentary for every president's inaugural address.

https://t.co/LR7wvnV8i0

2/


Digital manorialism vs neofeudalism: Tech companies as warlords with walled gardens.

https://t.co/uQ9rDCA8i3

3/


South Carolina GOP moots modest improvements to "magistrate judges": Lewis Carroll was an optimist.

https://t.co/1AQpZYwhOj

4/


Pavilions replacing union workers with "gig workers": Prop 22's other shoe drops.

https://t.co/hlX0A0S96c

5/