1. Yes, Trump will claim to intend to target GOP senators up for reelection in '22 (like he did to Thune with Kristi Noem) if they don't join in @HawleyMO's sedition on Jan. 6, but the fact is, it's not clear whether Trump will be successful in ANY of those efforts & voting yes
A lot of conversations today among Republican senators over move by @HawleyMO to challenge the certification of Biden\u2019s Electoral College victory. Small groups of Rs were huddling on & off the floor trying to game out the politics of what will happen Jan. 6
— John Bresnahan (@bresreports) January 1, 2021
We REALLY want to do what we can to encourage & grow resistance within the Rep Party itself to ripping up the Constitution. Symbolic or not, the things that they are doing MATTER and we are in a place, institutionally speaking,
More from Rachel "The Doc" Bitecofer 📈🔭🍌
For years Rs have had Ds on defense, crying "socialist!" while hiding a radicalism so extreme it seeks to destroy democracy itself.
— Rachel "The Doc" Bitecofer \U0001f4c8\U0001f52d\U0001f34c (@RachelBitecofer) January 11, 2021
That's why we're launching @StrikePac- its time to fight \U0001f525 with \U0001f525!
Strike back w STRIKE PAC
RT for democracy's sakehttps://t.co/xSVfNSqLNF https://t.co/O9q5mQXtE5
2. @MeidasTouch, @votevets & other "super pacs" which are essentially grassroots funded organizations that are making use of the "super pac" designation to electioneer. Organizing as a super pac actually affords groups a great deal of flexibility to perform pro-democracy work
3. so despite the "ewww, yuck!" factor of that designation, not all SP's are, in fact, evil entities (other than the fact that so many of you I wholly support a fully publicly funded system w very strict limits & honestly, a 30 day electioneering window per cycle which would
4. decimate a multi-billion $ industry BUT do a great deal of work to save our democracy & that type of system, by the way, is BY FAR, the norm among western democracies. Ours is literally the Wild West of electioneering systems and if there is 1 "fix all" reform that would have
5. the greatest & most immediate impact on pulling our democracy back from the precipice of our democracy it would be a fully publicly funded, tightly regulated election/campaigning system. We don't have one of those right now & if we ever want to reach the majorities that could
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@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 30, 2021
"we generated a mouse model expressing hACE2 by using CRISPR/Cas9 knockin technology. In comparison with wild-type C57BL/6 mice, both young & aged hACE2 mice sustained high viral loads... pic.twitter.com/j94XtSkscj
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 2, 2021
2 papers:
Human\u2013viral molecular mimicryhttps://t.co/irfH0Zgrve
Molecular Mimicryhttps://t.co/yLQoUtfS6s https://t.co/lsCv2iMEQz
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj

@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
