An Ode to 2020, as the end is drawing near.

You'd need 2020 vision, to predict this shocking year.

1/21

The year sea levels rose and forests burned around the world.

Events and sports suspended, but black voices finally heard.

2/21
The year when we were teachers and our kids all stayed at home.

And bubbles meant the lonely didn't have to be alone.

3/21
The year when we all starred online in our own celebrity squares.

We had Teams and we were Zooming but not going anywhere.

4/21
The year the Worm came back and NASA launched from US soil.

US astronauts on US rockets, reward for years of toil.

5/21
The year the virus spread and the scientists all tried.

To fast track through a vaccine while some politicians lied.

6/21
The year when two elections showed the public really cares.

New Zealand backed their leader while Americans fired theirs.

7/21
The year when we remembered who the heroes truly are.

Doctors, nurses, front line staff. Every one a star.

8/21
The year a comet came and some planets got together.

We took samples from an asteroid and watched the Martian weather.

9/21
The year when jobs were lost and we all learned what furlough meant.

As many others worked from home and landlords deferred rent.

10/21
The year we hoarded bog roll and learned how to sanitize.

And that storing tons of fertiliser close to fireworks isn't wise.

11/21
The year a football champion, took on a worthy cause.

And fought for children's lunches, and changes in the laws.

12/21
And the year a wartime hero took a step outside his door.

And raised millions by walking, arise Captain Sir Tom Moore.

13/21
The year of extreme weather, and many hurricanes.

Pubs closed and hotels empty and grounded aeroplanes.

14/21
The year we lost a telescope as Arecibo's dish.

Was crushed by falling steel and concrete. Everything got squished.

15/21
The year we learned to shop online and the delivery driver's name.

And that viruses don't care about your status, wealth or fame.

16/21
The year we thought we'd found the signs of life in clouds on Venus.

And twenty years on orbit showed what can be done between us.

17/21
The year self isolation wasn't just about your health.

As a European nation traded rights for fish and tax-free wealth.

18/21
The year when we lost loved ones, but couldn't say goodbye.

While engineers in Texas proved starships were meant to fly.

19/21
This year will be remembered for, though we'd all rather forget.

The tragic human cost which sadly isn't over yet.

20/21
But there is hope of a brighter future when the virus is finally gone.

Good riddance 2020. Bring on 2021.

21/21

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@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)

@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice


@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2


@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj


@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
1/ Some initial thoughts on personal moats:

Like company moats, your personal moat should be a competitive advantage that is not only durable—it should also compound over time.

Characteristics of a personal moat below:


2/ Like a company moat, you want to build career capital while you sleep.

As Andrew Chen noted:


3/ You don’t want to build a competitive advantage that is fleeting or that will get commoditized

Things that might get commoditized over time (some longer than


4/ Before the arrival of recorded music, what used to be scarce was the actual music itself — required an in-person artist.

After recorded music, the music itself became abundant and what became scarce was curation, distribution, and self space.

5/ Similarly, in careers, what used to be (more) scarce were things like ideas, money, and exclusive relationships.

In the internet economy, what has become scarce are things like specific knowledge, rare & valuable skills, and great reputations.