Meanwhile, a few days ago the EMA published its EPAR (public assessment report) on the Moderna vax (HT @pajz_) https://t.co/LHW4rGgFwV It's 169 pages ...1/n

...There was "a major objection" to the US manufacturing sites, so they were withdrawn. Complete transfer for Europe to Swiss manufacturing due to conclude soon. (There have been Qs in the US about a batch there https://t.co/g573j7uFNQ)...2/n
...If you're interested in the chemical & biological aspects of this vaccine, there are pages for you to dig into - not an area I have any expertise in. Small amount of detail of reproductive toxicity study (in rats): no cause for concern....3/n
...The clinical trial data is from November, as for the FDA data. There's more detail than in the FDA report, though, of the phase 2 study, which hasn't been published. 600 people: a lot of data on immunogenicity (but not cell-mediated immunity)...4/n
...More methodological data on blinding etc for the phase 3 trial & *a lot more data* than in the FDA report. And take a moment to appreciate this: 30,000 people enrolled in less than 3 months. Giant thank you's due all round ...5/n
...In my posts, I've pointed to FDA report someone with apparent severe Covid-19 not adjudicated or in Moderna's analyses. Now we know why: no cases before dose 2 & not all suspected ones were adjudicated. That's not reassuring, though they conclude "no substantial bias" ... 6/n
...Like FDA, EMA point to person with severe Covid-19 in the vaccine group. Overall, data on severity reassured them, but "the cases overall seem mostly mild, which is a limitation of the dataset". "No definitive conclusion on clinical efficacy after one dose can be drawn" ...7/n
...They also conclude the definition of severe Covid-19 "could have been more stringent from a clinical
perspective". They say open questions remain about the lower bound for the confidence interval of efficacy, partly because of the case ascertainment issue, so... 8/n
...they want more data in a final report by December 2022 before considering approval. Serious adverse events seem similar to FDA's conclusions (but I haven't cross-checked case by case). Apropos today's other discussion: 7,520 people were aged 65+...9/n
...Conclusion? This is a far better report than the FDA's one on this vaccine: it's the "go to". Not comfortable that the unadjudicated person with severe Covid signals a bigger issue, but very glad the EMA is on it. 10/10

More from Government

🔷 Rev. Raphael Warnock has become the first Democrat to win a Georgia Senate race in 20 years

The politician spoke to voters via MSNBC this morning

https://t.co/T9oJN2fjmo


Warnock is a pastor at the Ebenezer Baptist Church in Atlanta where civil rights leader Martin Luther King once preached.

He will become Georgia's first Black senator


This blue victory gives the Democrats the chance to regain control of the Senate for at least the first two years of the Biden presidency


"With Biden proposing to reverse President Donald Trump's tax cut, increase the minimum wage, and strengthen oversight on various industries, some might argue that his agenda is not particularly market-friendly," says Vasu Menon, investment strategy director at OCBC Bank

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THREAD: 12 Things Everyone Should Know About IQ

1. IQ is one of the most heritable psychological traits – that is, individual differences in IQ are strongly associated with individual differences in genes (at least in fairly typical modern environments). https://t.co/3XxzW9bxLE


2. The heritability of IQ *increases* from childhood to adulthood. Meanwhile, the effect of the shared environment largely fades away. In other words, when it comes to IQ, nature becomes more important as we get older, nurture less.
https://t.co/UqtS1lpw3n


3. IQ scores have been increasing for the last century or so, a phenomenon known as the Flynn effect. https://t.co/sCZvCst3hw (N ≈ 4 million)

(Note that the Flynn effect shows that IQ isn't 100% genetic; it doesn't show that it's 100% environmental.)


4. IQ predicts many important real world outcomes.

For example, though far from perfect, IQ is the single-best predictor of job performance we have – much better than Emotional Intelligence, the Big Five, Grit, etc. https://t.co/rKUgKDAAVx https://t.co/DWbVI8QSU3


5. Higher IQ is associated with a lower risk of death from most causes, including cardiovascular disease, respiratory disease, most forms of cancer, homicide, suicide, and accident. https://t.co/PJjGNyeQRA (N = 728,160)
Master Thread of all my threads!

Hello!! 👋

• I have curated some of the best tweets from the best traders we know of.

• Making one master thread and will keep posting all my threads under this.

• Go through this for super learning/value totally free of cost! 😃

1. 7 FREE OPTION TRADING COURSES FOR


2. THE ABSOLUTE BEST 15 SCANNERS EXPERTS ARE USING

Got these scanners from the following accounts:

1. @Pathik_Trader
2. @sanjufunda
3. @sanstocktrader
4. @SouravSenguptaI
5. @Rishikesh_ADX


3. 12 TRADING SETUPS which experts are using.

These setups I found from the following 4 accounts:

1. @Pathik_Trader
2. @sourabhsiso19
3. @ITRADE191
4.


4. Curated tweets on HOW TO SELL STRADDLES.

Everything covered in this thread.
1. Management
2. How to initiate
3. When to exit straddles
4. Examples
5. Videos on