Meanwhile, a few days ago the EMA published its EPAR (public assessment report) on the Moderna vax (HT @pajz_) https://t.co/LHW4rGgFwV It's 169 pages ...1/n

...There was "a major objection" to the US manufacturing sites, so they were withdrawn. Complete transfer for Europe to Swiss manufacturing due to conclude soon. (There have been Qs in the US about a batch there https://t.co/g573j7uFNQ)...2/n
...If you're interested in the chemical & biological aspects of this vaccine, there are pages for you to dig into - not an area I have any expertise in. Small amount of detail of reproductive toxicity study (in rats): no cause for concern....3/n
...The clinical trial data is from November, as for the FDA data. There's more detail than in the FDA report, though, of the phase 2 study, which hasn't been published. 600 people: a lot of data on immunogenicity (but not cell-mediated immunity)...4/n
...More methodological data on blinding etc for the phase 3 trial & *a lot more data* than in the FDA report. And take a moment to appreciate this: 30,000 people enrolled in less than 3 months. Giant thank you's due all round ...5/n
...In my posts, I've pointed to FDA report someone with apparent severe Covid-19 not adjudicated or in Moderna's analyses. Now we know why: no cases before dose 2 & not all suspected ones were adjudicated. That's not reassuring, though they conclude "no substantial bias" ... 6/n
...Like FDA, EMA point to person with severe Covid-19 in the vaccine group. Overall, data on severity reassured them, but "the cases overall seem mostly mild, which is a limitation of the dataset". "No definitive conclusion on clinical efficacy after one dose can be drawn" ...7/n
...They also conclude the definition of severe Covid-19 "could have been more stringent from a clinical
perspective". They say open questions remain about the lower bound for the confidence interval of efficacy, partly because of the case ascertainment issue, so... 8/n
...they want more data in a final report by December 2022 before considering approval. Serious adverse events seem similar to FDA's conclusions (but I haven't cross-checked case by case). Apropos today's other discussion: 7,520 people were aged 65+...9/n
...Conclusion? This is a far better report than the FDA's one on this vaccine: it's the "go to". Not comfortable that the unadjudicated person with severe Covid signals a bigger issue, but very glad the EMA is on it. 10/10

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How does a government put a legislation on 'hold'? Is there any constitutional mechanism for the executive to 'pause' a validly passed legislation? Genuine Koshan.


So a committee of 'wise men/women' selected by the SC will stand in judgement over the law passed by


Here is the thing - a law can be stayed based on usual methods, it can be held unconstitutional based on violation of the Constitution. There is no shortcut to this based on the say so of even a large number of people, merely because they are loud.


Tomorrow can all the income tax payers also gather up at whichever maidan and ask for repealing the income tax law? It hurts us and we can protest quite loudly.

How can a law be stayed or over-turned based on the nuisance value of the protestors? It is anarchy to allow that.
I am going to take the context for this thread from this piece by my good brother @mabziz in 2018-3 years ago. One thing I am so perturbed about is the response of our Attorney General's office to issues of state security. I have no personal grouse against @MalamiSan, but


2. I do have a professional grouse against him. I feel he is not alive to his duties. I feel that he is also not empowering his Director of Public Prosecutions or his Solicitor General. There is clearly a lot that befuddles me and this is because I am a seasoned lawyer and can't/

3. understand why law is not being used as the instrument it was designed for-to enforce law and order. Let us take the case of Nnamdi Kanu-this man was arraigned in Nigeria on a charge of treason/treasonable felony-he was on bail & he jumped bail. Why has he not been extradited?

4. Is it that Kanu is somehow bigger than Nigeria? What has happened to his surety who failed to produce him? Who is prosecuting him? Our Federal Ministry of Justice? Should Malami not explain to Nigeria why Nnamdi Kanu is still taunting Nigeria daily & still actively destroying/

5. our unity everyday. He is putting the lives of many people at risk and stoking ethnic dissent easily. The Fulani herdsmen dilemma, the burning of Lagos State and his coordination of same on phone-in radio channels, his videos are all stoking a Yoruba/Igbo carnage. Same with/

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