1/ Total freedom isn't always your friend.

I always thought the goal was 100% location independence, where I can pick and choose anywhere to live. This has it's perks for sure, but it has more drawbacks than I'd like to admit.

2/ I've lived in 3 countries over 24 months (unintentional nomad). Currently looking for a place to get permanent residence and plant some long-term roots in LATAM.
3/ I've been on-the-ground in 7 LATAM countries, and tbh the more cities I visit, the harder it is for me to know where it is I should be.
4/ There's not a ton holding me to any one place now that my team works remotely, and every place on earth, no matter how perfect, has it's drawbacks.
5/ If I take an in-office job I really want in a place that's 70% optimal, it's easier IMO to commit to that place than if I'm working remotely in a place that's 90% optimal. Why? Because there's real consequences if I decide to leave (losing the job).
6/ As an expat especially, the grass always seems greener somewhere else. That constant allure of the next cool place can distract you from sticking with a place once the honeymoon phase is over.
7/ Comitting required developing strong personal relationships with locals very quickly.
8/ For example: First place outside of US I lived was KL Malaysia...Not optimal in many ways (weather, air quality, more urban than my family wanted) but we quickly built a group of friends, who introduced us to all the great things about the city
9/ We got out of the expat bubble fast, which meant those personal relationships were longer lasting (as expats are rarely permanent residents).
10/ We felt a strong connection to the city very fast, and that made it easier to overlook the things we didn't love and invest more in the area.

In Costa Rica it was slightly different. Beyond my cofounder, I didn't have as strong a friends group as in Malaysia.
11/ The startup scene is weaker here so fewer people to talk shop with than in SEA. I'm more familiar with the culture here and the language than in SEA, but the volume of meaningful relationships with locals matters a lot.
12/ Now as I make decisions on where to live permanently over the next decade, I'm not just looking at places where my wife and kids will be happy, but also places that tie me down.
13/ Freedom is awesome, but 100% freedom makes it difficult to committ, and committment to a place has a big affect on happiness when you're past the rush of moving around a ton.

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राम-रावण युद्ध समाप्त हो चुका था। जगत को त्रास देने वाला रावण अपने कुटुम्ब सहित नष्ट हो चुका था।श्रीराम का राज्याभिषेक हुआ और अयोध्या नरेश श्री राम के नेतृत्व में चारों दिशाओं में शन्ति थी।
अंगद को विदा करते समय राम रो पड़े थे ।हनुमान को विदा करने की शक्ति तो राम में थी ही नहीं ।


माता सीता भी हनुमान को पुत्रवत मानती थी। अत: हनुमान अयोध्या में ही रह गए ।राम दिनभर दरबार में, शासन व्यवस्था में व्यस्त रहते थे। संध्या को जब शासकीय कार्यों में छूट मिलती तो गुरु और माताओं का कुशल-मंगल पूछ अपने कक्ष में जाते थे। परंतु हनुमान जी हमेशा उनके पीछे-पीछे ही रहते थे ।


उनकी उपस्थिति में ही सारा परिवार बहुत देर तक जी भर बातें करता ।फिर भरत को ध्यान आया कि भैया-भाभी को भी एकांत मिलना चाहिए ।उर्मिला को देख भी उनके मन में हूक उठती थी कि इस पतिव्रता को भी अपने पति का सानिध्य चाहिए ।

एक दिन भरत ने हनुमान जी से कहा,"हे पवनपुत्र! सीता भाभी को राम भैया के साथ एकांत में रहने का भी अधिकार प्राप्त है ।क्या आपको उनके माथे पर सिन्दूर नहीं दिखता?इसलिए संध्या पश्चात आप राम भैया को कृप्या अकेला छोड़ दिया करें "।
ये सुनकर हनुमान आश्चर्यचकित रह गए और सीता माता के पास गए ।


माता से हनुमान ने पूछा,"माता आप अपने माथे पर सिन्दूर क्यों लगाती हैं।" यह सुनकर सीता माता बोलीं,"स्त्री अपने माथे पर सिन्दूर लगाती है तो उसके पति की आयु में वृद्धि होती है और वह स्वस्थ रहते हैं "। फिर हनुमान जी प्रभु राम के पास गए ।
https://t.co/6cRR2B3jBE
Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.

https://t.co/FBfXhUrH5d


Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.


...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.


Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.