Certain “experts” should be quite ashamed for pushing fear mongering tweets and using misleading studies to fit their rhetoric concerning the efficacy of these vaccines. Since they rely on the fact most will not understand the studies since it’s not in layman’s terms allow me. 🧵

Firstly, the conclusions being drawn from this study and this “expert” is that the B.1.1.7 and B.1.351 variants would render these vaccines ineffective. This is highly unlikely. It will take a large amount of genetic diversity to completely render the current vaccines useless.

Not to mention Ding is using an older study to push this rhetoric when Pfizer and Moderna have recently established their vaccines will be effective against these variants. Perhaps someone should pass THOSE studies onto him. For the record, if you’re going to claim these vaccines

are ineffective the last thing you should attempt to utilize to push your rhetoric is a study that concerns monoclonal antibodies. Why? Vaccines are polyclonal. Unlike monoclonal antibody therapies, vaccines (especially those utilizing the whole spike protein) make polyclonal

antibody responses. This means that the antibodies you make after vaccination will be able to bind the coronavirus spike in multiple places not just one. You cannot possibly attempt to relate the effectiveness of a monoclonal antibody treatment against these variants to the

The importance of T-cell immunity!
A recent study has found that after one dose of Pfizer’s vaccine, patients had a strong T-cell response, and a boosted antibody response after their second dose. This is good news for many reasons so let’s read up.

This study found that people’s antibodies were moderately effective against the original strain after their first dose of Pfizer’s vaccine, less effective against the B.1.1.7 variant, and were unable to neutralize the B.1.351 variant. Read what I said, that’s only after ONE dose.

However, they had strong T-cell responses against ALL known variants after the first dose. So why is this important? To recap, T-cells stimulate B-cells to make antibodies. Antibodies are just your first line of defense which is what is initiated when you get a vaccine.

It’s our T-cells that are responsible for long-term immunity. When antibodies diminish after your initial inoculation, your T-cells-will tell your B-cells it’s time to produce more antibodies. As long as your T-cells still recognize this virus and inform your B-cells they need

to produce antibodies, the vaccine is still doing its job. Your antibodies will get built up over and over again. Just FYI your TCRs and your BCRs target different parts of the Coronavirus’ spike protein. Antibodies can prevent infection, your T cell-responses ensure that those

Undoubtedly there is going to be a lot of conversation surrounding the new viral variants. This is me being completely transparent when I say this: please don’t panic. The most important thing we can do is prevent the virus from spreading. Let me elaborate.

It will take a large amount of genetic diversity to completely render these vaccines useless. These mutations have not been able to alter the S protein’s shape to the extent that the vaccine-induced antibodies provided by these vaccines are not able to bind at all.

Remember these vaccines (especially these using the whole spike protein) make polyclonal antibody responses. This means that the antibodies created will be able to bind the Coronavirus’ spike in multiple places not just one. Hence a broader range of protection even with changes.

We have many tools to prevent the virus from spreading. Physical barriers (masks), social distancing, and proper hand hygiene. We also have effective vaccines that need to be used immediately. We want and need more protected people and fewer susceptible people. Simple as that.

If the virus doesn’t spread it doesn’t mutate. It needs us, as a host, and our cells to do this. If we don’t give it that, it can’t spread nor mutate. With the vaccines, if the neutralizing activity of vaccine sera goes down too much the vaccines can be replaced and modified.

Them: Is there any other vaccine in history that required three doses in a year and yet still didn’t prevent transmission of the virus it was meant to protect against?

Me: Your childhood vaccinations would like a word with you.

Before I forget, reminder that your TDap: Tetanus-Diphtheria-Pertussis (every 10 years) are technically a repetitive vaccine series or rather boosters during adulthood. HPV is another vaccine that could fit here as well.

“Even the measles vaccine, which is incredibly effective, fails to protect about 3% of vaccinated individuals who are exposed to the virus. Jonas Salk's polio vaccine-hailed a medical miracle- was 80% to 90% effective at preventing paralysis caused by the polio virus.”

“Breakthrough cases don’t mean that the vaccines aren’t