Wanna disable Defender when enabled Isolated Core and Tamper protection?

Its a bit more trouble- but doable, without ruining Isolated Core/Secureboot etc.

Defenders process will run as a unkillable protected service- so new tricks needed.

Here we go:

Ok- tamper protection is easy, just make .bat - run as adm:
:again
reg add "HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\WdFilter\Instances\WdFilter Instance" /v altitude /t REG_SZ /d -1 /f
goto again

Then unload minifilter with process hacker:

The registry key will be changed while the minifilter do not protect it, when tamper protection makes the driver load again it cannot attach to volumes nor protect registry keys.

Removing it will make it recreate, but invalid altitude do the trick

Notice now the service is: Protected light(antimalware)
Now we cant do anything to the service/process- not even see its open handles.

Lets start by elevating to SYSTEM- just launch a command prompt, then close process hacker- and run it again from the command prompt.
Now process hacker runs as SYSTEM