Sufficient niacin supply: the missing puzzle piece to COVID-19, and beyond?

Dmitry Kats, Ph.D., M.P.H.*

* Correspondence: [email protected]

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Abstract: Definitive antiviral properties are evidenced for niacin, i.e., nicotinic acid (NA), as coronavirus disease 2019 (COVID-19) therapy for both health restoration and prevention, to the level that progression of COVID-19 pathology may follow as an intrinsic function of NA

supply. This detailed investigation proposes thorough disentanglement of how the downstream inflammatory propagation of ensuing severe acute respiratory virus 2 (SARS-CoV-2) infection can either be prohibited or reversed upstream out the body to expeditiously restore health with

well-tolerated dynamic supplementation of sufficient NA (i.e., ~1-3 grams per day). Culmination of this research leads to realization of the potentially ubiquitous therapeutic and preventive powers of NA against inflammatory disease, in general.

Despite continued intensive efforts to mitigate the spread and burden of coronavirus disease 2019 (COVID-19) in populations, implications for the future remain unclear. Encouraging nonetheless is the vast understanding of the disease gained as a result of the unprecedented level