https://t.co/RbqZKkUIjx
Controversial 3D. Probably none of you knows about Leber congenital amaurosis type 10, congenital blindness that affects 3 out of 100,000 children, condemning them to blindness for life. The only possible treatment is through gene therapy. 1/n
https://t.co/RbqZKkUIjx
https://t.co/iO2jqcIxU0
https://t.co/mG9lQoNCXI
https://t.co/gnczyUWw9i
https://t.co/nYLR1Sq2BW
So take a small risk to protect the others and stop complaining. 9/n
#WearADamnMask #vaccinoCovid 10/10
More from Health
1/15
Why can cefepime cause neurological toxicity?
And why is renal failure the main risk factor for this complication?
The answer requires us to learn about cefepime's structure and why it unexpectedly binds to a certain CNS receptor.
#MedTwitter #Tweetorial
2/
Let's establish a few facts about cefepime:
🔺4th generation cephalosporin antibiotic
🔺Excretion = exclusively in the urine (mostly as unchanged drug)
🔺Readily crosses the blood-brain barrier (so it easily accesses the brain)
https://t.co/rjYG1BfGPR
3/
The first report of cefepime neurotoxicity was in 1999.
A patient w/ renal failure received high doses of cefepime and then developed encephalopathy, tremors, myoclonic jerks, and tonic-clonic seizures.
✅All symptoms resolved after hemodialysis.
https://t.co/u7JLVitQpp
4/
Cefepime neurotoxicity is surprisingly common, occurring in up to 15% of treated critically ill patients (w/ symptoms varying from encephalopathy to seizures).
💡The main risk factors = renal failure and lack of dose adjustment for renal function.
https://t.co/nxbnzSq8AR
5/
What about cefepime induces neurotoxicity?
One clue is that it's not the only antibiotic that causes neurotoxicity, particularly seizures.
This actually is a class effect w/ other beta-lactam antibiotics (including penicillins and carbapenems).
https://t.co/Lf4BhON9IY
Why can cefepime cause neurological toxicity?
And why is renal failure the main risk factor for this complication?
The answer requires us to learn about cefepime's structure and why it unexpectedly binds to a certain CNS receptor.
#MedTwitter #Tweetorial
2/
Let's establish a few facts about cefepime:
🔺4th generation cephalosporin antibiotic
🔺Excretion = exclusively in the urine (mostly as unchanged drug)
🔺Readily crosses the blood-brain barrier (so it easily accesses the brain)
https://t.co/rjYG1BfGPR
3/
The first report of cefepime neurotoxicity was in 1999.
A patient w/ renal failure received high doses of cefepime and then developed encephalopathy, tremors, myoclonic jerks, and tonic-clonic seizures.
✅All symptoms resolved after hemodialysis.
https://t.co/u7JLVitQpp
4/
Cefepime neurotoxicity is surprisingly common, occurring in up to 15% of treated critically ill patients (w/ symptoms varying from encephalopathy to seizures).
💡The main risk factors = renal failure and lack of dose adjustment for renal function.
https://t.co/nxbnzSq8AR
5/
What about cefepime induces neurotoxicity?
One clue is that it's not the only antibiotic that causes neurotoxicity, particularly seizures.
This actually is a class effect w/ other beta-lactam antibiotics (including penicillins and carbapenems).
https://t.co/Lf4BhON9IY
Thread on how atheism leads to mental retardation (backed with medical citations🧵💉)
To start with, atheism is an unnatural self-contradicting doctrine.
Medical terminology proves that human beings are naturally pre-disposed to believe in God. Oxford scientists assert that people are "born believers".
https://t.co/kE0Fi588yn
https://t.co/OqyXcGIMJn
It should be known that atheism could never produce an intelligently-functioning society and neither ever will.
Contrastingly, Islam produced several intellectuals & polymaths, was on the forefront of scientific development, boasting 100% literacy
It is also scientifically proven that atheism led to lesser scientific curiosity and scientific frauds, which is also why atheists incline to pseudo-science.
Whereas, religion in general and Islam in particular boosted education.
https://t.co/19Onc84u3g
Atheists are also likely to affected by pervasive mental and developmental disorders like high-functioning autism.
Cognitive Scientists and renowned Neurologists found that more atheism is leads to greater autism.
https://t.co/zRjEyFoX3P
To start with, atheism is an unnatural self-contradicting doctrine.
Medical terminology proves that human beings are naturally pre-disposed to believe in God. Oxford scientists assert that people are "born believers".
https://t.co/kE0Fi588yn
https://t.co/OqyXcGIMJn
It should be known that atheism could never produce an intelligently-functioning society and neither ever will.
Contrastingly, Islam produced several intellectuals & polymaths, was on the forefront of scientific development, boasting 100% literacy
If the Muslim world had not existed, there literally would be no technology/achievements today.
— Starks\u262a\ufe0f\U0001f1f9\U0001f1e9 (@MegaIntelIect) January 8, 2021
Science only developed because of Islam, Europe should be grateful to Islam for civilizing their barbaric cult.
Source: The Caliph's Splendor, Pg 204-05 https://t.co/HVypO52Tpc pic.twitter.com/00jYSbaDSs
It is also scientifically proven that atheism led to lesser scientific curiosity and scientific frauds, which is also why atheists incline to pseudo-science.
Whereas, religion in general and Islam in particular boosted education.
https://t.co/19Onc84u3g
Atheists are also likely to affected by pervasive mental and developmental disorders like high-functioning autism.
Cognitive Scientists and renowned Neurologists found that more atheism is leads to greater autism.
https://t.co/zRjEyFoX3P