THREAD: Gorilla Troop Comms

These people are

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Thread of decodes for the day. Make sure you check out the [SUB] threads too!

#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…

Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.

Axovant Lifescience, bought Alzheimer molecule from GSK, repackaged it and done phase-3 trials. Before starting the trials, the valuation was $2 Bn, just before announcing the data, it rose to $3 Bn. One of the leading broker put the target of $12 Bn if the trials succeeded..

but it failed in phase-3 trials. Current Mcap is $120 Mn…

This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…

Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range

from Alzheimer’s, dementia, epilepsy, migraine, multiple sclerosis, neuro infections, Parkinson’s, psychosis, schizophrenia and stroke to brain injuries and various mental disorders. The global market or CNS therapeutics is projected to reach $137.7 billion by 2025.

#SuvenLife has 1 lead molecule SUVN-G3031 in phase-2 trials which is similar to Xyrem but superior features, 3 molecules completed phase-1 trials and starting phase-2 trials and 11 molecules in pre-clinical trials. All are related to CNS which is growing and uncluttered market

@jeffreyatucker In the end, it is all a natural consequence of a very human foible, namely that we all do everything we can to blame anybody or anything else for our problems, if we can get away with it. It's the reason why rulers start wars to squelch domestic dissent - macro and micro the same

The very notion of the germ theory of disease revolves around this and while it is good for selling medical interventions, treatments and pharmaceuticals, it is no good for either personal health, or public health in any way. We need to start looking at health on a holistic level

More of a systems approach to health would get us to see that the whole instinct to stamp out viruses, like the very counter-factual notion of "zero Covid," and other nonsense, are driven by this need to blame somebody or something else for our problems, so we can have our cake

and eat it too, i.e. we can pass the blame to others and go and kill them, be they bugs or other people (lockdowns???). The results are disastrous for health on both a personal and a public level, and we continue on a path of assured self-destruction. But times are changing, now.

Lifestyle Medicine @aclifemed provides the new paradigm, more of a systems approach to health, in which personal responsibility for our habits comes first, starting with nutrition. Immune systems become depressed by fatigue, stress, inner conflict, malnutrition and so on. Change

My view on lent:

My biggest problem with lent is the public display of fasting which is contrary to scripture: Matthew 6:16-18

Just as well, overhearing discussions of humble brags, “oh man, this is so hard fasting from x” while displaying ashes on one’s forehead seems overtly contrary to scripture. Again, Matthew 6:16-18 is clear.

Additionally it has been my experience that repentance and fasting lose much of their substance for those practicing the tradition.

However....

We cannot oversimplify and call lent a “Roman Catholic invention” or a “pagan” practice given its presence, minimally the term, in the early church with people like Athanasius.

In the modern conception: Advent is to Christmas what lent is to Easter. While asceticism is removed and shallow tradition enters into the practice, this can happen in most everything.

Back when I went to Bishop’s University, I managed the student radio station, CJMQ. When I started, it was kind of a pirate station. We had an illegal antenna on a roof, and a couple of residences could get us through the radiators somehow. Nowhere to go but up.

Happily, it was 1993. Pump Up the Volume made it cool to be a DJ. Grunge and indie were huge. We went from, like, 12 DJs to 100 and started acting like a real radio station. God, it was awesome. It was like we were on a quest. It felt like a real crusade.

Eventually we decided to try to get an FM licence. This was no easy feat. The bureaucracy was maddening. It cost a lot. We needed to find a proper tower. Long story short, after two years of solid effort, everything came together: CJMQ was awarded 88.9 on your FM dial.

We were going to launch one blissful night in 1995. I planned a massive party and woke up the morning of, not quite believing we’d finally made it. I went to say good morning to my roommate, David, and… Not a single sound came out of my mouth. Not even a whisper.

I had completely and utterly lost my voice. OH GOD NO. I raced to the pharmacy and scribbled a note to the pharmacist: “I’ve lost my voice, and I really need my voice.” She nodded and retrieved two suppositories. They were each the size of large-caliber artillery shells.