How did you improve your "content diet" this year?
Spending time with family for the holidays?
Here are 10 thought-provoking questions guaranteed to spark an interesting dinner conversation.
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How did you improve your "content diet" this year?
He adds, “Hard work is a prison sentence only if it does not have meaning.”
Do you feel this way about your work today?
When's the last time you did this?
It's a psychological tool that helps people reason & see the situation from a slight distance
When have you used an alter ego to reduce anxiety & gain confidence?
Anytime you have a small window where your heart rate isn't spiking, you open your phone for a dopamine hit.
Boredom can actually enable creativity by allowing the mind to wander & daydream.
When is the last time you felt bored?
Research shows that the language we speak can influence our thinking, giving us wildly different perspectives of the world.
How has the language you speak shaped your identity?
“A smile, a head nod, even just grunting to show you’re listening—those are all positive,” John Gottman says.
How many positive interactions have you & your partner had today?
Every time you label someone, you filter what you see.
Who is someone you can see through a lens of nuance?
Chef Grant Achatz decided he wanted to open the best restaurant in the country. "Anything else would be a failure."
What is the biggest, boldest, most ambitious goal you could conceive of?
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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs