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Turns out that getting chemo is like sending cancer to a relaxing spa getaway for the weekend, so that it comes back refreshed and ready to kill.
That's disturbing.
What else have we misunderstood?
Biological sex and cancer.
A short thread.
1/7
Almost every type of cancer affects men more than women. And overall, more women survive a cancer diagnosis. Men also develop about 150,000 extra cancers per year in the US, compared to women.
Why is that?
Because biology.
2/7
We used to think that the reason for female cancer 'resistance' was behaviorally based because: women see their doctor more often and drink less alcohol etc.
But that's not the whole story.
3/7
Women have two X chromosomes while men have only one. We used to think that women's 2nd X was 'silenced' and not able to work for them.
But this is also wrong.
And the so called 'silenced' X isn't silent at all. Women actually have the use of both X chromosomes.
4/7
Some of the genes involved in cancer suppression are on the X chromosome. And a 2nd copy of these genes is only available to women because they have two X chromosomes.
When it comes to preventing cancer women have more genetic horsepower in each of their cells.
5/7
That's disturbing.
What else have we misunderstood?
Biological sex and cancer.
A short thread.
1/7
Out now! #Cancer cells can enter a quiescent state in response to #chemotherapy and subsequently emerge rejuvenated https://t.co/sw9UTbgDPX @UHN @UHN_Research pic.twitter.com/xAIcxAcQJM
— Cell (@CellCellPress) January 7, 2021
Almost every type of cancer affects men more than women. And overall, more women survive a cancer diagnosis. Men also develop about 150,000 extra cancers per year in the US, compared to women.
Why is that?
Because biology.
2/7
We used to think that the reason for female cancer 'resistance' was behaviorally based because: women see their doctor more often and drink less alcohol etc.
But that's not the whole story.
3/7
Women have two X chromosomes while men have only one. We used to think that women's 2nd X was 'silenced' and not able to work for them.
But this is also wrong.
And the so called 'silenced' X isn't silent at all. Women actually have the use of both X chromosomes.
4/7

Some of the genes involved in cancer suppression are on the X chromosome. And a 2nd copy of these genes is only available to women because they have two X chromosomes.
When it comes to preventing cancer women have more genetic horsepower in each of their cells.
5/7
