1/Part 2 on #diabetes #prevention based on the @TheLancet diabetes commission report.

Individual level prevention of type 2 diabetes (T2D) gets a lot of attention. Part 2 reflect this - but don’t worry, there will be more on the other levels in part 3..

Let’s get going..

2/Several large randomized controlled trials (RCT) have shown that lifestyle interventions (diet, exercise, metformin) can prevent/delay onset of T2D as well as prevent later complications like cardiovascular disease and eye disease.

3/This has led to the implementation of diabetes prevention programmes for people at high risk of T2D in some high-income countries (HIC) like Germany, Finland, USA, UK, Poland and Singapore.

4/Evaluation of such real-world interventions is important as they may not provide similar benefits as in the RCTs that included volunteers that were very closely supervised. Evaluation of the US DPP has observed favorable weight loss at 1 year. Similar efforts are underway in UK

5/Although the individual level interventions overall work when there is adherence, it is often only a small proportion of the population that can adhere over time. Hence...