We are belatedly entering the hearing.

Ian Wise is setting out arguments.

#StopStonewall

#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…

Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.

Axovant Lifescience, bought Alzheimer molecule from GSK, repackaged it and done phase-3 trials. Before starting the trials, the valuation was $2 Bn, just before announcing the data, it rose to $3 Bn. One of the leading broker put the target of $12 Bn if the trials succeeded..

but it failed in phase-3 trials. Current Mcap is $120 Mn…

This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…

Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range

from Alzheimer’s, dementia, epilepsy, migraine, multiple sclerosis, neuro infections, Parkinson’s, psychosis, schizophrenia and stroke to brain injuries and various mental disorders. The global market or CNS therapeutics is projected to reach $137.7 billion by 2025.

#SuvenLife has 1 lead molecule SUVN-G3031 in phase-2 trials which is similar to Xyrem but superior features, 3 molecules completed phase-1 trials and starting phase-2 trials and 11 molecules in pre-clinical trials. All are related to CNS which is growing and uncluttered market

The ten points of the Nuremberg Code
1) The voluntary consent of the human subject is absolutely essential.

2) The experiment should be such as to yield fruitful results for the good of society, unprocurable by other methods or means of study, and not random and unnecessary in nature. 2/n

3) The experiment should be so designed and based on the results of animal experimentation and a knowledge of the natural history of the disease or other problem under study that the anticipated results will justify the performance of the experiment. 3/n

4) The experiment should be so conducted as to avoid all unnecessary physical and mental suffering and injury. 4/n

5) No experiment should be conducted where there is an a priori reason to believe that death or disabling injury will occur; except, perhaps, in those experiments where the experimental physicians also serve as subjects. 5/n

[42c] I’M CALLING IT ANONS.

I'M CALLING THE DEATH OF QUEEN ELIZABETH II ON 12/27/2020

THREAD POSTED ON DECEMBER 14, 2020

DECEMBER 14, DEC 1+4, D5.

PART ##4 CHESS 4D
PART ##5 CHESS 5D

d4.d5 FaLL of THE QUEEN

[13] DAYS TO PROVE ME WRONG

People! Have you seen people being rude to each other during meetings, maybe directed at women/people of colour/disabled people/LGBTQ+ people? Do you want to help prevent this abuse?

Some tips you can consider as a bystander depending on the situation (thread)

Have a code of conduct and circulate it. Make it clear that abusive behaviour will not be accepted. Build in accountability strategies (what happens if someone violates it). Have a moderator/chair to observe the dynamics of your group.

This kind of behaviour is very normalised and insidious, so train yourself to spot it. Is there somebody that usually interrupts? Is there somebody that usually gets interrupted and silenced? Are there signs of aggressive communication?

Not everyone might like that you jump at their defense - your heart might be in the right place but it can come across as patronising. Try to bring up the subject with your colleagues and see what they think. Foster a culture of positive communication.

Once you see that somebody is trying to interrupt - politely redirect the discussion towards the person that was originally speaking. Eg "thank you for that, now I'd really like to hear what person xyz was saying earlier".

@DawgLaser @GravelInstitute Rush Hudson Limbaugh III (/ˈlɪmbɔː/ LIM-baw; January 12, 1951 – February 17, 2021) was an American radio personality, conservative political commentator, author, and television show host.