#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…
Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.
This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…
Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range
SUVN-502 has recently failed in phase-2 trials where it couldn’t meet the primary end points related to Alzheimer’s but sub group studies has revealed some interesting statistically significant and
potentially beneficial effects of masupirdine on cognition,
of behavioural and psychological symptoms of dementia (BPSD). Market size for this could be $2 Bn for USA.
This molecule addresses a rare disease – Excessive Daytime Sleepiness (EDS) – in narcoleptic patients
3. SUVN-D4010 (phase-1 completed)
This molecule works for better cognition and as an anti-depressant
It addresses the biggest limitations of current major depressive disorder (MDD) therapeutics with rapid onset of action, no sexual dysfunction, and enhancement in cognition
Some of the listed companies on NASDAQ working in CNS, (though not
More from jeevan patwa
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Pompeo New Year's Resolution - America First threads
Thread ⬇️⬇️⬇️
https://t.co/YDGI6CZIsA
Thread ⬇️⬇️⬇️
https://t.co/YDGI6CZIsA
I've been watching since NYE and while I was digging and decoding last night I put this together and noticed some breaks in the tweets - Notice Podesta and HK...https://t.co/VdARL0dn20
— History_Maker (@JaimeLynnFusco) January 14, 2021
This response to my tweet is a common objection to targeted advertising.
@KevinCoates correct me if I'm wrong, but basic point seems to be that banning targeted ads will lower platform profits, but will mostly be beneficial for consumers.
Some counterpoints 👇
1) This assumes that consumers prefer contextual ads to targeted ones.
This does not seem self-evident to me
Research also finds that firms choose between ad. targeting vs. obtrusiveness 👇
If true, the right question is not whether consumers prefer contextual ads to targeted ones. But whether they prefer *more* contextual ads vs *fewer* targeted
2) True, many inframarginal platforms might simply shift to contextual ads.
But some might already be almost indifferent between direct & indirect monetization.
Hard to imagine that *none* of them will respond to reduced ad revenue with actual fees.
3) Policy debate seems to be moving from:
"Consumers are insufficiently informed to decide how they share their data."
To
"No one in their right mind would agree to highly targeted ads (e.g., those that mix data from multiple sources)."
IMO the latter statement is incorrect.
@KevinCoates correct me if I'm wrong, but basic point seems to be that banning targeted ads will lower platform profits, but will mostly be beneficial for consumers.
Some counterpoints 👇
That targeted ads allow for "free" products for consumers is a common talking point and we're going to see more of it in the coming months.: https://t.co/Xty3My3f0u (1/14)
— Kevin Coates (@KevinCoates) February 16, 2021
1) This assumes that consumers prefer contextual ads to targeted ones.
This does not seem self-evident to me
Great post by @Sherman1890 got me thinking about the future of targeted ads.
— Dirk Auer (@AuerDirk) February 12, 2021
More and more tools (privacy labels, ad blockers, GDPR) enable consumers to opt-out from targeted ads - can limit the data platforms receive or block ads altogether.
The end of targeted ads? \U0001f9f5\U0001f447 https://t.co/MA6A3BrUWq
Research also finds that firms choose between ad. targeting vs. obtrusiveness 👇
If true, the right question is not whether consumers prefer contextual ads to targeted ones. But whether they prefer *more* contextual ads vs *fewer* targeted
2) True, many inframarginal platforms might simply shift to contextual ads.
But some might already be almost indifferent between direct & indirect monetization.
Hard to imagine that *none* of them will respond to reduced ad revenue with actual fees.
3) Policy debate seems to be moving from:
"Consumers are insufficiently informed to decide how they share their data."
To
"No one in their right mind would agree to highly targeted ads (e.g., those that mix data from multiple sources)."
IMO the latter statement is incorrect.
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Fake chats claiming to be from the Irish African community are being disseminated by the far right in order to suggest that violence is imminent from #BLM supporters. This is straight out of the QAnon and Proud Boys playbook. Spread the word. Protest safely. #georgenkencho
There is co-ordination across the far right in Ireland now to stir both left and right in the hopes of creating a race war. Think critically! Fascists see the tragic killing of #georgenkencho, the grief of his community and pending investigation as a flashpoint for action.
Across Telegram, Twitter and Facebook disinformation is being peddled on the back of these tragic events. From false photographs to the tactics ofwhite supremacy, the far right is clumsily trying to drive hate against minority groups and figureheads.
Declan Ganley’s Burkean group and the incel wing of National Party (Gearóid Murphy, Mick O’Keeffe & Co.) as well as all the usuals are concerted in their efforts to demonstrate their white supremacist cred. The quiet parts are today being said out loud.
The best thing you can do is challenge disinformation and report posts where engagement isn’t appropriate. Many of these are blatantly racist posts designed to drive recruitment to NP and other Nationalist groups. By all means protest but stay safe.
There is co-ordination across the far right in Ireland now to stir both left and right in the hopes of creating a race war. Think critically! Fascists see the tragic killing of #georgenkencho, the grief of his community and pending investigation as a flashpoint for action.
Across Telegram, Twitter and Facebook disinformation is being peddled on the back of these tragic events. From false photographs to the tactics ofwhite supremacy, the far right is clumsily trying to drive hate against minority groups and figureheads.
Be aware, the images the #farright are sharing in the hopes of starting a race war, are not of the SPAR employee that was punched. They\u2019re older photos of a Everton fan. Be aware of the information you\u2019re sharing and that it may be false. Always #factcheck #GeorgeNkencho pic.twitter.com/4c9w4CMk5h
— antifa.drone (@antifa_drone) December 31, 2020
Declan Ganley’s Burkean group and the incel wing of National Party (Gearóid Murphy, Mick O’Keeffe & Co.) as well as all the usuals are concerted in their efforts to demonstrate their white supremacist cred. The quiet parts are today being said out loud.
There is a concerted effort in far-right Telegram groups to try and incite violence on street by targetting people for racist online abuse following the killing of George Nkencho
— Mark Malone (@soundmigration) January 1, 2021
This follows on and is part of a misinformation campaign to polarise communities at this time.
The best thing you can do is challenge disinformation and report posts where engagement isn’t appropriate. Many of these are blatantly racist posts designed to drive recruitment to NP and other Nationalist groups. By all means protest but stay safe.
