Authors Billy Bostickson πŸ΄πŸ‘&πŸ‘ πŸ†“

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Tip from the Monkey
Pangolins, September 2019 and PLA are the key to this mystery
Stay Tuned!


1. Yang


2. A jacobin capuchin dangling a flagellin pangolin on a javelin while playing a mandolin and strangling a mannequin on a paladin's palanquin, said Saladin
More to come tomorrow!


3. Yigang Tong
https://t.co/CYtqYorhzH
Archived: https://t.co/ncz5ruwE2W


4. YT Interview
Some bats & pangolins carry viruses related with SARS-CoV-2, found in SE Asia and in Yunnan, & the pangolins carrying SARS-CoV-2 related viruses were smuggled from SE Asia, so there is a possibility that SARS-CoV-2 were coming from
@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)

@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice


@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2


@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj


@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
1/X Bellagio Rockefeller Initiative (Global Virome Project)
Another look at some key people in the GVP & their media statements since January 2020 about "natural origin" and impossibility of a "lab leak"
Full List of 18 scientists in photograph is here:
https://t.co/yHoAjwQjI8


2/X
We have already looked closely at Dennis Carroll, Peter Daszak, George Gao, W. Ian Lipkin & seen their public statements supporting "natural origin" & hysterical attacks on "lab leak" theories.
This thread focuses on:
Michael Kurilla
Jonna Mazet
Edward Rubin (Metabiota)

3/X
If we look at the leadership team of GVP, you will see some familiar faces:
https://t.co/WdT8sNnfmy
Most familiar is probably Peter Daszak, the wealthy Treasurer, also with the key role of Secretary.
Note: USAID PREDICT Project - EcoHealthAlliance


4/X
The "Chair" is Dr. Dennis Carroll
We will have a look at his media statements on the coronavirus pandemic by inputting his name in Twitter search box (very easy!)
Note: Previously was Director of USAID Emerging Pandemic Threats Program


5/X Dennis Carroll's video media statements (1):
CNN
(note Qinghai Thangka positioned in background which Daszak also shows off in his videos obtained during EcoHealth virus hunt with
Same covid-19 mutations are appearing in different places, which may or may not be strange....
41,000 mutations documented in 880 lineages.
Most in spike protein
What explains it?


https://t.co/MvHzUb4peo


https://t.co/PAwgC3lgsO


https://t.co/f9rnyFI0vq


https://t.co/wAlyNzuI0W
@snip96581187 @Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen Clearly, because as I have been saying for 8 months now, DTRA and DARPA have been using Ecohealth and UC Davis to collect novel pathogens for gain of function work back in the USA. I have documented this in many threads which I will post here just to annoy everyone.

@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen


@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen


@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen


@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
2 papers:
Human–viral molecular mimicry
https://t.co/irfH0Zgrve
Molecular Mimicry
https://t.co/yLQoUtfS6s

2. Must Read! Confirmation with supporting evidence via @flavinkins
https://t.co/NEf9HK6ReB
"ONLY place where this thing could emerge, naturally or Artificially, is by passage in HUMANIZED MICE"

3. Springer Article


4. Takeaway most significant quotes from Springer Article, burn this into your brain:
"Such a peptide commonality is unexpected and highly improbable from a mathematical point of view"


5. One image to explain it all!
Emergent Bio-Kramer-BARDA-HHS-Kadlec-Fauci
U.S. Bet Big on Covid Vaccine Manufacturer Even as Problems Mounted https://t.co/o2lbFoXF5U
β€œViral cross-contamination confirmed in the control cells for JANSSEN GMP Lot #8.”


an examination by The @nytimes of manufacturing practices at the Baltimore facility found serious problems, including a corporate culture that often ignored or deflected missteps and a government sponsor, BARDA, that acted more as a partner than a policeman."


https://t.co/3TszTYVhry


https://t.co/ng1oV1xrKI


https://t.co/TNQMo8LZ83
"The coronavirus in Italy since September 2019"
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy
First Published November 11, 2020
https://t.co/nhlccks5AS
Smashed Paywall thanks to @Sci_Hub
https://t.co/wWPFJMjjFJ

Maybe a coincidence but an agreement was recently signed by the authors' institute and guess who?
https://t.co/vh7qX3hyPD


The Lead Author specifically of the paper:
"Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy"
is Giovanni Apolone of the "Fondazione IRCCS Istituto Nazionale Tumori" Milan, Italy


Some funding is involved....
Anyone good at Italian feel free to comment?


"You findee sars cov 2 in old sample back September time, we give you big fat red envelopeee, okey dokey?"

More has emerged regarding the Chinese connection
"Oncology research, Italy and China close to the collaboration protocol"
.https://t.co/Mt5hO9Dggc
PCR Drosten Fail Compilation
1. Ten Fatal Errors: Scientists Attack Paper That Established Global PCR Driven Lockdown
https://t.co/25p88F2xu6
2. Review report Corman-Drosten et al.
https://t.co/8rlT4MWoyI
3. Consequences of false

PCR Drosten Fail Compilation
4. Files for download
https://t.co/SqDrZjB9em
5. Addendum
https://t.co/IygCWvnAsP
6. False positives in reverse transcription PCR testing for SARS-CoV-2
https://t.co/HxpSZkzZ7Q
7. Discussion on Retraction

PCR Drosten Fail Compilation
8. 124 Tweet Thread by Bobby Rajesh Malhotra
@Bobby_Network
https://t.co/cdot5yIeuf
9. Another shorter thread by @Bobby_Network
https://t.co/kqFW9GsSeD
10. Thread by Abir Ballan

PCR Drosten Fail Compilation
11. Mini Thread by @Kevin_McKernan
https://t.co/pntydnd80L
12. Another longer thread by @Kevin_McKernan
https://t.co/5hBYIlXFnQ
13.
Zhengli Shi and Deyin Guo in 2015
Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Increase or Decrease Replication and Pathogenesis
https://t.co/YMlsqFOvZp


Deyin Guo 2016:
Molecular mechanisms of coronavirus RNA capping and methylation
https://t.co/xdEU5goLB6


Deyin Guo 2012
Short peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2β€²-O-methyltransferase activity of nsp10/nsp16 complex
https://t.co/x30jPYFDTa


Deyin Guo 2013
Structure-function Analysis of SARS Coronavirus RNA Cap Guanine-N7 Methyltransferase.
https://t.co/NG57b85hcs


Deyin Guo 2016
Identification and Characterization of a Ribose 2’-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales
https://t.co/zZ5V7erseD
1. Updated Thread on:
A, Wuhan Seafood Market Positive Environmental Samples, B. Early Local Reports about Animals at the Market
C. CCP Censorship and Police harassment of local activists uploading censored news reports to GitHub.
The original thread was a mess!

2. CCP Censorship & Police harassment of local activists uploading censored news reports to GitHub.
It all started with a simple search query:
"market" "animal" on a github database:
https://t.co/q2HxuUuHKa
Only to find that it had been deleted on github due to CCP pressure!

3. Github is Censorship proof, right?
It does not get deleted! But..
https://t.co/k7BJWUgWDq
Arms get Twisted!
https://t.co/ckzicj7NlE
Please remember these brave young activists for creating a permanent record of censored news from the early days while CCP rewrites history


4. What a shock!
But thanks to the very nature of GitHub, "forks" and "clones" had been made & saved.
The best one is here:
https://t.co/ZWiyWK9SAa
Obviously all in Chinese ;) but tks to Google Chrome we can right click translate to English & find archived scrubbed Chinese news


5. "This is an archive of in-depth reports and personal narratives on the COVID-19 outbreak in China"
Contains media reports, non-fictional works and personal narratives related to the 2020 coronavirus pneumonia.
Part of the archive is provided by netizens, I am grateful.
1/ Directed Evolution and Serial passage of RNA Viruses
A quick (I hope) thread on RNA viruses & some others, mainly for my own learning process, but also as evidence (as if it was needed) of what modern virology & microbiology is capable of doing to viruses in their laboratories

2/ In Vivo Continuous Directed Evolution
1 Recent advances in the field of in vivo continuous evolution
2 Advances in continuous culture of microbes enable continuous evolution
3 Viruses, prokaryotes, & eukaryotes mediate in vivo continuous evolution
https://t.co/BfR0B2Hwsf


3/ Continuous Directed Evolution of Biomolecules
By greatly accelerating laboratory evolution, PACE may provide solutions to otherwise intractable directed evolution problems and address novel questions about molecular evolution.
https://t.co/G3mIptI54H


4/ CDE for Strain & Protein Engineering
Inducible hypermutator systems accelerate strain evolution without compromising genome integrity.
Site-specific in vivo mutagenesis strategies have facilitated continuous protein engineering.
Automation

5/ Targeted mutagenesis:
A sniper-like diversity generator in microbial engineering
https://t.co/wdKyXghRYe
Advances in the directed evolution of proteins
https://t.co/1xXTtw1i3i
In vivo continuous directed evolution
https://t.co/xKRVSjVvo4
1. Some useful, albeit not fully developed, critiques of:

β€œThe Origins of SARS-CoV-2: A Critical Review"

https://t.co/C9TyRyqHUr

have just been published here:
https://t.co/qCmzGCzRxn
by members of DRASTIC & others
@angoffinet @BahulikarRahul @MonaRahalkar @gdemaneuf

2. A refreshing contrast to the so-called "expert reactions" found here, including from one of the authors of the review (Prof David Robertson)!

"expert reaction to a preprint reviewing the evidence on the origins of SARS-CoV-2"

https://t.co/6kG6rstweP


3. Peter Gutierrez points out in his response that 4 of the authors of β€œThe Origins of SARS-CoV-2: A Critical Review”, also wrote β€œProximal Origin of SARS-COV-2”.

His critique focuses on:

1. RaTG13

2. Enhanced adaptation to the human host

https://t.co/eW8b2iK5xe


4. As to be expected, Sydney University and its iconic virologist, Eddie Holmes, who is "not available for interview", are crowing over this biased review
https://t.co/xrjpN1NxpO


This review contains elementary errors as exposed here:
1. https://t.co/YJ50huifly
one of the authors (Stuart Neil) then claimed
"Didn’t N501Y come up in ACE2 TG mice too?
https://t.co/HscNSEKdrZ
@jimmy_wales Thanks for replying!
1/. I will make a thread here with some details so you can see for yourself how a small clique of pro Chinese gatekeeping editors and admins have bullied editors, throttled dissent and gamed the system to impose their POV.

2/. I am a supporter of


3/. This is what I ended up feeling about WP after


4/. Some disturbing


5./ Some members of the gatekeeping
1. Omicron Thread - A Compilation of Opinions

"finally, the time has slip and slid its slimy course through to us - and we're the vicious bastards of the new generation. we do not relent, and we should not be held to account for our ancestral faults"

https://t.co/mhJO6yOQRE


2. The Letter Chosen by the WHO

"It's amazing that the Xi variant seems to have somehow managed to evade detection..."

via @readomain

Why 'Omicron', Not 'Nu' or 'Xi'?

WHO Says Two Letters in Greek Alphabet Jumped to 'Avoid Stigma'

https://t.co/xnGR9XK2tF


3. The Omicron variant has been found in nearly every province of South Africa, as well as Botswana, Belgium, Israel, UK and Hong Kong.

This month, Israel held an exercise, The β€œOmega Exercise”, meant to prepare for a hypothetical, new COVID-19

4. Omicron Infographic

(appeared in Germany and Italy now)

https://t.co/oNFYBH1F1o


5. Overview of Omicron (B.1.1.529) from @nicd_sa

https://t.co/HN9csJqK0z
1. Thread: RaTG13 Real or Fake?
A Norwegian Scientist @Vehuardo recently claimed RaTG13 is an "authentic virus"
https://t.co/tAXMNTwdhA
This failed to take into account the work of our DRASTIC colleagues & other published analyses.
This thread is a polite attempt to educate.

2.
https://t.co/tw606vgHwp
which says RaTG13 doesn't make sense on how it was sequenced, or how the data got so messed up in the lab as to include copy paste mistakes, bat dna, pangolin dna, rice dna, mice dna, & nobody should use it to form conclusions until it's properly vetted

2 (cont)
"sequence is incomplete & provided segment doesn't function. The identified markers suggest partial match basis & actual virus itself as described by the sequence can't functionally exist due to incoherent structures that appear to be the result of sample contamination"


3. RaTG13 integrity is further attacked here:
The Validity of critical pieces of evidence for the natural origin of SARS-CoV-2 is Dubious, and needed to be

4. and here:
Major Concerns on the Identification of Bat Coronavirus Strain RaTG13 and Quality of Related Nature