Open letter to journal editors: dynamite plots must die. Dynamite plots, also known as bar and line graphs, hide important information. Editors should require authors to show readers the data and avoid these plots. https://t.co/0GNKEIUCJL pic.twitter.com/OS9ytEFRZN
— Rafael Irizarry (@rafalab) February 22, 2019
"The new answer to a 77-year-old problem"
😭
The new answer to a 77-year-old problem in data analysis, published today in @naturemethods. Instead of significance tests, use estimation graphics. Our software suite DABEST makes it easy for everyone to visualize effect sizes.https://t.co/UzwXJ7EUC5 pic.twitter.com/VtxyY0xaRM
— Adam Claridge-Chang (@adamcchang) June 19, 2019
Couldn't find D3 code for grouped horisontal box plots that show data points so I made this @mbostock @thisisalfie https://t.co/cQjDPhyZdw pic.twitter.com/y6RNmDB2p3
— Ulrik Lyngs (@ulyngs) June 28, 2017
made a pkg for pirate plots in ggplot: add any of points/means/bars/CIs/violins \u2013 better than ye olde bar/box plotshttps://t.co/Z2m2kW3hsl pic.twitter.com/npAirPQexM
— Mika Braginsky (@mbraginsky) September 28, 2017
See the new #PowerBI visual awesomeness for data points & sources, box-&-whisker plots! https://t.co/dOmgoxWfDE pic.twitter.com/HAUOAMJEJW
— Microsoft Power BI (@MSPowerBI) February 1, 2016
On bar/line graphs, & data presentation. Need for strict data treatment https://t.co/8aqICdCX9K @PLOSBiology pic.twitter.com/KQkYKdmWq7
— Crisanto Gutierrez (@CG_ath) November 30, 2015
\U0001f62e pretty stoked on this PR in the pipeline\u2026
— Mara Averick (@dataandme) May 10, 2018
"Nonstandard aesthetics" by @ClausWilke {ggplot2} https://t.co/X9hkxX44jo #rstats #dataviz pic.twitter.com/gKlEU8Gxa3
Perceptions of probability https://t.co/9xsr6FUR2e shown by @amandacox #openvisconf pic.twitter.com/hJsYY7ggB3
— Rob Simmon (@rsimmon) April 25, 2017
Ok. https://t.co/ifP2RNpLIn
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Hard agree. And if this is useful, let me share something that often gets omitted (not by @kakape).
Variants always emerge, & are not good or bad, but expected. The challenge is figuring out which variants are bad, and that can't be done with sequence alone.
You can't just look at a sequence and say, "Aha! A mutation in spike. This must be more transmissible or can evade antibody neutralization." Sure, we can use computational models to try and predict the functional consequence of a given mutation, but models are often wrong.
The virus acquires mutations randomly every time it replicates. Many mutations don't change the virus at all. Others may change it in a way that have no consequences for human transmission or disease. But you can't tell just looking at sequence alone.
In order to determine the functional impact of a mutation, you need to actually do experiments. You can look at some effects in cell culture, but to address questions relating to transmission or disease, you have to use animal models.
The reason people were concerned initially about B.1.1.7 is because of epidemiological evidence showing that it rapidly became dominant in one area. More rapidly that could be explained unless it had some kind of advantage that allowed it to outcompete other circulating variants.
Variants always emerge, & are not good or bad, but expected. The challenge is figuring out which variants are bad, and that can't be done with sequence alone.
Feels like the next thing we're going to need is a ranking system for how concerning "variants of concern\u201d actually are.
— Kai Kupferschmidt (@kakape) January 15, 2021
A lot of constellations of mutations are concerning, but people are lumping together variants with vastly different levels of evidence that we need to worry.
You can't just look at a sequence and say, "Aha! A mutation in spike. This must be more transmissible or can evade antibody neutralization." Sure, we can use computational models to try and predict the functional consequence of a given mutation, but models are often wrong.
The virus acquires mutations randomly every time it replicates. Many mutations don't change the virus at all. Others may change it in a way that have no consequences for human transmission or disease. But you can't tell just looking at sequence alone.
In order to determine the functional impact of a mutation, you need to actually do experiments. You can look at some effects in cell culture, but to address questions relating to transmission or disease, you have to use animal models.
The reason people were concerned initially about B.1.1.7 is because of epidemiological evidence showing that it rapidly became dominant in one area. More rapidly that could be explained unless it had some kind of advantage that allowed it to outcompete other circulating variants.
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Funny, before the election I recall lefties muttering the caravan must have been a Trump setup because it made the open borders crowd look so bad. Why would the pro-migrant crowd engineer a crisis that played into Trump's hands? THIS is why. THESE are the "optics" they wanted.
This media manipulation effort was inspired by the success of the "kids in cages" freakout, a 100% Stalinist propaganda drive that required people to forget about Obama putting migrant children in cells. It worked, so now they want pics of Trump "gassing children on the border."
There's a heavy air of Pallywood around the whole thing as well. If the Palestinians can stage huge theatrical performances of victimhood with the willing cooperation of Western media, why shouldn't the migrant caravan organizers expect the same?
It's business as usual for Anarchy, Inc. - the worldwide shredding of national sovereignty to increase the power of transnational organizations and left-wing ideology. Many in the media are true believers. Others just cannot resist the narrative of "change" and "social justice."
The product sold by Anarchy, Inc. is victimhood. It always boils down to the same formula: once the existing order can be painted as oppressors and children as their victims, chaos wins and order loses. Look at the lefties shrieking in unison about "Trump gassing children" today.
Funny there are those who think these migrant caravans were a FANTASTIC idea that's going to take the immigration issue away from you.
— Brian Cates (@drawandstrike) November 26, 2018
Like several weeks watching a rampaging horde storm the fences & throw rocks at our border patrol agents & getting gassed = great optics!
This media manipulation effort was inspired by the success of the "kids in cages" freakout, a 100% Stalinist propaganda drive that required people to forget about Obama putting migrant children in cells. It worked, so now they want pics of Trump "gassing children on the border."
There's a heavy air of Pallywood around the whole thing as well. If the Palestinians can stage huge theatrical performances of victimhood with the willing cooperation of Western media, why shouldn't the migrant caravan organizers expect the same?
It's business as usual for Anarchy, Inc. - the worldwide shredding of national sovereignty to increase the power of transnational organizations and left-wing ideology. Many in the media are true believers. Others just cannot resist the narrative of "change" and "social justice."
The product sold by Anarchy, Inc. is victimhood. It always boils down to the same formula: once the existing order can be painted as oppressors and children as their victims, chaos wins and order loses. Look at the lefties shrieking in unison about "Trump gassing children" today.
