But for others, the shift from a distributor model to importer/exporter has been a challenge. This hasn't been helped by certain IT system not working as planned.
1/ Quick thread. At the end of the third week of Brexit being "done", I can only say that I'm exhausted.
Immediate pressures on companies who have been trading goods have been on grappling with all of the new customs and regulatory requirements.
But for others, the shift from a distributor model to importer/exporter has been a challenge. This hasn't been helped by certain IT system not working as planned.
Some are, but many others aren't.
Worth noting that freight volumes are still below average. But stockpiles are running low, coming weeks are going to be interesting.
First, many businesses are facing the largest shift in their cost base in a generation.
This is something that is going to be something that will continue to play and play in the weeks and months ahead.
For many, the answer will be no. So what do they do as a result?
The other (worse) possibility is to stop trading.
https://t.co/IMDCu9g2mK
Supply chains are going to shift as a result and is deeply complex.
But that's just one example
Absolutely not.
One such example: due to the pandemic, business travel isn't happening. All the changes that are coming down the line in the activities which individuals can carry out while in the EU has changed.
More from Brexit
Another head-banging day for the £112bn UK creative sector that is starting to ingest how difficult #Brexit is going to make their lives - and how little the government is really willing to do to fix the lack of a 'mobility' chapter in the EU-UK trade deal. Quick update.../1
First Equity @EquityUK put out a letter to @BorisJohnson warning that #brexit was a "towering hurdle" (you'd want Brian Blessed reading that part) to UK actors plying their trade in EU - a double whammy with #COVID19 /2
https://t.co/mXjTAISqZk
@BorisJohnson One third of Equity members say they've seen job ads asking for EU passport holders: "Before, we were able to travel to Europe visa-free. Now we have to pay hundreds of pounds, fill in form after form, and spend weeks waiting for approval" /3
@BorisJohnson Worth recalling that all this goes back to the UK desire NOT to have a 'mobility' provision within the TCA - all part of 'ending Free Movement' and the professional services folk - including musicians, actors, fashion models etc -are all victim of
@BorisJohnson What's the government going to do about all this? Good question, which brings us to todays @CommonsDCMS hearing in which the Culture Minister Caroline Dinenage @cj_dinenage frankly pin-balled around the issues /5
First Equity @EquityUK put out a letter to @BorisJohnson warning that #brexit was a "towering hurdle" (you'd want Brian Blessed reading that part) to UK actors plying their trade in EU - a double whammy with #COVID19 /2
https://t.co/mXjTAISqZk
@BorisJohnson One third of Equity members say they've seen job ads asking for EU passport holders: "Before, we were able to travel to Europe visa-free. Now we have to pay hundreds of pounds, fill in form after form, and spend weeks waiting for approval" /3
@BorisJohnson Worth recalling that all this goes back to the UK desire NOT to have a 'mobility' provision within the TCA - all part of 'ending Free Movement' and the professional services folk - including musicians, actors, fashion models etc -are all victim of
@BorisJohnson What's the government going to do about all this? Good question, which brings us to todays @CommonsDCMS hearing in which the Culture Minister Caroline Dinenage @cj_dinenage frankly pin-balled around the issues /5
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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs